miRNA: a promising therapeutic target in cancer
microRNAs are small non-coding RNAs that regulate several genes post-transcriptionally by
complementarity pairing. Since discovery, they have been reported to be involved in a …
complementarity pairing. Since discovery, they have been reported to be involved in a …
Therapeutic microRNA strategies in human cancer
Abstract MicroRNAs (miRNAs) are~ 22 nucleotide long, noncoding, endogenous RNA
molecules which exert their functions by base pairing with messenger RNAs (mRNAs) …
molecules which exert their functions by base pairing with messenger RNAs (mRNAs) …
Targeting microRNAs in cancer gene therapy
W Ji, B Sun, C Su - Genes, 2017 - mdpi.com
MicroRNAs (miRNAs) are a kind of conserved small non-coding RNAs that participate in
regulating gene expression by targeting multiple molecules. Early studies have shown that …
regulating gene expression by targeting multiple molecules. Early studies have shown that …
microRNA therapeutics in cancer—an emerging concept
MY Shah, A Ferrajoli, AK Sood, G Lopez-Berestein… - …, 2016 - thelancet.com
MicroRNAs (miRNAs) are an evolutionarily conserved class of small, regulatory non-coding
RNAs that negatively regulate protein coding gene and other non-coding transcripts …
RNAs that negatively regulate protein coding gene and other non-coding transcripts …
MicroRNA as an important target for anticancer drug development
Z Fu, L Wang, S Li, F Chen, KKW Au-Yeung… - Frontiers in …, 2021 - frontiersin.org
Cancer has become the second greatest cause of death worldwide. Although there are
several different classes of anticancer drugs that are available in clinic, some tough issues …
several different classes of anticancer drugs that are available in clinic, some tough issues …
Targeting microRNAs in cancer: rationale, strategies and challenges
MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs that regulate
gene expression. Early studies have shown that miRNA expression is deregulated in cancer …
gene expression. Early studies have shown that miRNA expression is deregulated in cancer …
Therapeutic targeting of microRNAs in cancer: future perspectives
ABSTRACT Preclinical Research The discovery of microRNAs (miRNAs) and their link with
cancer has opened a new era in cancer therapeutics. Approximately, 18− 24 nucleotides …
cancer has opened a new era in cancer therapeutics. Approximately, 18− 24 nucleotides …
microRNA therapies in cancer
SI Rothschild - Molecular and cellular therapies, 2014 - Springer
MicroRNAs (miRNAs or miRs) are a family of small non-coding RNA species that have been
implicated in the control of many fundamental cellular and physiological processes such as …
implicated in the control of many fundamental cellular and physiological processes such as …
Recent trends in targeting miRNAs for cancer therapy
Objectives MicroRNAs (miRNAs) are a type of small noncoding RNA employed by the cells
for gene regulation. A single miRNA, typically 22 nucleotides in length, can regulate the …
for gene regulation. A single miRNA, typically 22 nucleotides in length, can regulate the …
microRNAs as cancer therapeutics: A step closer to clinical application
TC Ivkovic, G Voss, H Cornella, Y Ceder - Cancer letters, 2017 - Elsevier
During the last decades, basic and translational research has enabled great improvements
in the clinical management of cancer. However, scarcity of complete remission and many …
in the clinical management of cancer. However, scarcity of complete remission and many …