Resistance to fluconazole (FLC), the most widely used antifungal drug, is typically achieved
by altering the azole drug target and/or drug efflux pumps. Recent reports have suggested a …

Small molecules are components of fungal extracellular vesicles (EVs), but their biological
roles are only superficially known. NOP16 is a eukaryotic gene that is required for the activity …

Small molecules are components of fungal extracellular vesicles (EVs), but their biological
roles are only superficially known. NOP16 is a eukaryotic gene that is required for the activity …

Cryptococcus neoformans causes deadly mycosis in immunocompromised individuals.
Macrophages are key cells fighting against microbes. Extracellular vesicles (EVs) are cell-to …

Extracellular vesicles (EVs) are produced by all domains of life. In fungi, these structures
were first described in Cryptococcus neoformans and, since then, they were characterized in …

Whereas extracellular vesicle (EV) research has become commonplace in different
biomedical fields, this field of research is still in its infancy in mycology. Here we provide a …

Cryptococcus neoformans is a human pathogenic fungus that mainly afflicts
immunocompromised patients. One of its virulence strategies is the production of …

Cryptococcus neoformans produces extracellular vesicles containing a variety of cargo,
including virulence factors. To become extracellular, these vesicles not only must be …

Extracellular vesicles (EVs) are lipidic nanosized particles that deliver a highly complex
molecular cargo between cells and organisms and may serve numerous functions in …

Highlights•A major threat to human health are pathogenic fungi.•There is now burgeoning
evidence that fungi release extracellular vesicles (EVs), which may have a profound impact …