[PDF][PDF] The role of inflammation modulation in dental pulp regeneration

SH Zaky, M Shehabeldin, H Ray, C Sfeir - Eur Cell Mater, 2021 - ecmjournal.org
A vital and healthy dental pulp (DP) is required for teeth to remain functional throughout a
lifespan. Appreciating its value for the tooth, the regeneration of the DP is a highly …

Pulp capping materials modulate the balance between inflammation and regeneration

T Giraud, C Jeanneau, C Rombouts, H Bakhtiar… - Dental Materials, 2019 - Elsevier
The interrelations between inflammation and regeneration are of particular significance
within the dental pulp tissue inextensible environment. Recent data have demonstrated the …

Dental regeneration and materials—a partnership

AJ Smith, PJ Lumley, PL Tomson, PR Cooper - Clinical oral investigations, 2008 - Springer
Considerable focus on the biocompatibility of dental materials over the last three decades
has provided a platform for a wealth of studies on the cellular and molecular responses of …

Inflammatory and immunological aspects of dental pulp repair

M Goldberg, JC Farges, S Lacerda-Pinheiro… - Pharmacological …, 2008 - Elsevier
The repair of dental pulp by direct capping with calcium hydroxide or by implantation of
bioactive extracellular matrix (ECM) molecules implies a cascade of four steps: a moderate …

Inflammation–regeneration interplay in the dentine–pulp complex

PR Cooper, Y Takahashi, LW Graham, S Simon… - Journal of dentistry, 2010 - Elsevier
OBJECTIVES: Dental tissue disease and trauma provides an excellent model for the
interaction between tissue defence and regenerative processes and has application to many …

Scaffolds to control inflammation and facilitate dental pulp regeneration

JS Colombo, AN Moore, JD Hartgerink… - Journal of endodontics, 2014 - Elsevier
In dentistry, the maintenance of a vital dental pulp is of paramount importance because teeth
devitalized by root canal treatment may become more brittle and prone to structural failure …

Molecular mediators of pulp inflammation and regeneration

PR Cooper, AJ Smith - Endodontic Topics, 2013 - Wiley Online Library
Dental tissue infection results in immune and inflammatory responses mediated by
molecular and cellular events that, if unchecked, result in tissue breakdown. The tooth, like …

Is pulp inflammation a prerequisite for pulp healing and regeneration?

M Goldberg, A Njeh, E Uzunoglu - Mediators of inflammation, 2015 - Wiley Online Library
The importance of inflammation has been underestimated in pulpal healing, and in the past,
it has been considered only as an undesirable effect. Associated with moderate …

Complement activation by pulp capping materials plays a significant role in both inflammatory and pulp stem cells' recruitment

T Giraud, P Rufas, F Chmilewsky, C Rombouts… - Journal of …, 2017 - Elsevier
Introduction The role of complement, especially through the C5a fragment, is well-known for
the initiation of inflammation. Its involvement in regeneration has been shown more recently …

Preserving the vital pulp in operative dentistry: 1. a biological approach

AJ Smith, PJ Lumley - Dental update, 2002 - magonlinelibrary.com
This is the first in a series of four papers aimed at understanding human pulpal responses to
tissue injury, cavity preparation and restorative events. This article provides an insight into …