Zinc sequestration: arming phagocyte defense against fungal attack

KS Vignesh, JA Landero Figueroa, A Porollo… - PLoS …, 2013 - journals.plos.org
The innate immune system employs various defense mechanisms to combat invading
microbes. From a pathogen perspective, access to adequate nutrition is one of the …

Immunological orchestration of zinc homeostasis: the battle between host mechanisms and pathogen defenses

KS Vignesh, GS Deepe Jr - Archives of biochemistry and biophysics, 2016 - Elsevier
The importance of Zn ions (Zn) in regulating development and functions of the immune
system is well established. However, recent years have witnessed a surge in our knowledge …

Nutrient zinc at the host–pathogen interface

ZR Lonergan, EP Skaar - Trends in biochemical sciences, 2019 - cell.com
Zinc is an essential cofactor required for life and, as such, mechanisms exist for its
homeostatic maintenance in biological systems. Despite the evolutionary distance between …

Zinc at the host–fungus interface: How to uptake the metal?

LW Soares, AM Bailão, CMA Soares, MGS Bailão - Journal of Fungi, 2020 - mdpi.com
Zinc is an essential nutrient for all living organisms. However, firm regulation must be
maintained since micronutrients also can be toxic in high concentrations. This notion is …

Zinc homeostasis at the bacteria/host interface—from coordination chemistry to nutritional immunity

J Wątły, S Potocki… - Chemistry–A European …, 2016 - Wiley Online Library
Zinc is one of the most important metal nutrients for species from all kingdoms, being a key
structural or catalytic component of hundreds of enzymes, crucial for the survival of both …

Nutritional immunity: targeting fungal zinc homeostasis

OF Alamir, RO Oladele, C Ibe - Heliyon, 2021 - cell.com
Transition metals, such as Zn 2+, are essential dietary constituents of all biological life,
including mammalian hosts and the pathogens that infect them. Therefore, to thrive and …

An element of life: competition for zinc in host-pathogen interaction

H Haase - Immunity, 2013 - cell.com
An Element of Life: Competition for Zinc in Host-Pathogen Interaction: Immunity Skip to Main
Content Skip to Main Menu Advertisement Immunity This journal offers authors two options (open …

Essential role of zinc and zinc transporters in myeloid cell function and host defense against infection

M Sapkota, DL Knoell - Journal of immunology research, 2018 - Wiley Online Library
Zinc is an essential micronutrient known to play a vital role in host defense against
pathogens. Diets that are deficient in zinc lead to impaired immunity and delayed recovery …

An alloy of zinc and innate immunity: Galvanising host defence against infection

JB von Pein, CJ Stocks, MA Schembri… - Cellular …, 2021 - Wiley Online Library
Innate immune cells such as macrophages and neutrophils initiate protective inflammatory
responses and engage antimicrobial responses to provide frontline defence against …

Roles of zinc signaling in the immune system

S Hojyo, T Fukada - Journal of immunology research, 2016 - Wiley Online Library
Zinc (Zn) is an essential micronutrient for basic cell activities such as cell growth,
differentiation, and survival. Zn deficiency depresses both innate and adaptive immune …