Noncoding RNAs in cancer development

CP Lin, L He - Annual review of cancer biology, 2017 - annualreviews.org
It is becoming increasingly clear that a large repertoire of noncoding RNAs (ncRNAs) are
actively transcribed from the mammalian genome, regulating diverse cellular processes in …

lncRNA/MicroRNA interactions in the vasculature

MD Ballantyne, RA McDonald… - Clinical Pharmacology & …, 2016 - Wiley Online Library
MicroRNA (miRNA) have gained widespread attention for their role in diverse vascular
processes including angiogenesis, apoptosis, proliferation, and migration. Despite great …

MicroRNAs as novel regulators of angiogenesis

Y Suárez, WC Sessa - Circulation research, 2009 - Am Heart Assoc
MicroRNAs are short noncoding RNAs that function as negative regulators of gene
expression. Posttranscriptional regulation by miRNAs is important for many aspects of …

The role of microRNA in tumor invasion and metastasis

M Xia, MH Hu - Journal of cancer molecules, 2010 - airitilibrary.com
Invasion and metastasis are the hallmarks of malignant tumors differing from benign
diseases. Most of cancer deaths are mainly due to the development of tumor metastasis …

Involvement of lncRNAs and macrophages: potential regulatory link to angiogenesis

Y Jia, Y Zhou - Journal of Immunology Research, 2020 - Wiley Online Library
Macrophages are involved in angiogenesis, an essential process for organ growth and
tissue repair, and could contribute to the pathogenesis of angiogenesis‐related diseases …

[HTML][HTML] Long non-coding RNAs as communicators and mediators between the tumor microenvironment and cancer cells

D Chen, T Lu, J Tan, H Li, Q Wang, L Wei - Frontiers in oncology, 2019 - frontiersin.org
Long non-coding RNAs (lncRNAs) are a class of more than 200 nucleotides RNA transcripts
which have limited protein coding capacity. They regulate numerous biological processes in …

[HTML][HTML] LncRNAs and the angiogenic switch in cancer: clinical significance and therapeutic opportunities

P Mabeta, R Hull, Z Dlamini - Genes, 2022 - mdpi.com
Angiogenesis is one of the hallmarks of cancer, and the establishment of new blood vessels
is vital to allow for a tumour to grow beyond 1–2 mm in size. The angiogenic switch is the …

[HTML][HTML] Non-coding RNAs in lung cancer: emerging regulators of angiogenesis

Y Liao, X Wu, M Wu, Y Fang, J Li, W Tang - Journal of Translational …, 2022 - Springer
Lung cancer is the second cancer and the leading cause of tumor-related mortality
worldwide. Angiogenesis is a crucial hallmark of cancer development and a promising target …

[HTML][HTML] MicroRNAs in tumor endothelial cells: Regulation, function and therapeutic applications

Y Gu, MA Becker, L Müller, K Reuss, F Umlauf, T Tang… - Cells, 2023 - mdpi.com
Tumor endothelial cells (TECs) are key stromal components of the tumor microenvironment,
and are essential for tumor angiogenesis, growth and metastasis. Accumulating evidence …

[HTML][HTML] Non-Coding RNAs and Cancer

M Yıldız, O Erbaş - Journal of Experimental and Basic Medical Sciences, 2021 - jebms.org
Non-coding RNAs (ncRNAs) are actively transcribed by regions of the mammalian
transcriptome that do not encode proteins. ncRNAs are divided into several groups, the most …