Long non-coding RNA (lncRNA) genes have recently been discovered as key regulators of
developmental, physiological, and pathological processes in humans. Recent studies …

The switch from the normal quiescent vasculature to angiogenesis in tumors is induced by a
variety of growth factors, released from cancer and stromal cells upon oxygen and nutrients …

MicroRNAs (miRNAs) are a class of small noncoding RNA molecules containing only 20–22
nucleotides. MiRNAs play a role in gene silencing and translation suppression by targeting …

Background: Out of 3 billion base pairs in human genome only~ 2% code for proteins; and
out of 180,000 transcripts in human cells, about 20,000 code for protein, remaining 160,000 …

Noncoding RNAs (ncRNAs) constitute the majority of the human transcribed genome. This
largest class of RNA transcripts plays diverse roles in a multitude of cellular processes, and …

Colorectal cancer (CRC) is one of the leading causes of cancer mortality. Angiogenesis is a
rate-determining step in CRC development and metastasis. The balance of angiogenic and …

Although non-coding RNAs (ncRNAs) were initially thought to be a class of RNA transcripts
with no encoding capability, it has been established that some ncRNAs actually contain …

A relatively well-understood multistep process enables mutation-bearing cells to form
primary tumours, which later use the circulation system to colonize new locations and form …

Non-coding RNA refers to a large group of endogenous RNA molecules that have no protein
coding capacity, while having specialized cellular and molecular functions. They possess …

Recent large-scale transcriptome analyses have revealed that the human genome contains
more than just protein-coding genes. Indeed, a large number of transcripts, including long …