MicroRNAs and Long Non-Coding RNAs as Novel Targets in Anti-Cancer Drug Development

Y Baran - Current Pharmaceutical Biotechnology, 2023 - ingentaconnect.com
Non-coding RNAs comprise the majority of RNAs that have been transcribed from the
human genome, and these non-coding RNAs have essential regulatory roles in the cellular …

Methods for the study of long noncoding RNA in cancer cell signaling

Y Feng, X Hu, Y Zhang, D Zhang, C Li… - Cancer Cell Signaling …, 2014 - Springer
With the advances in sequencing technology and transcriptome analysis, it is estimated that
up to 75% of the human genome is transcribed into RNAs. This finding prompted intensive …

A review on theragnostic applications of microRNAs and long non-coding RNAs in colorectal cancer

G Jothimani, S Sriramulu, Y Chabria… - Current topics in …, 2018 - ingentaconnect.com
Colorectal cancer (CRC) is a heterogeneous malignancy leading to increased mortality and
poor prognosis due to the lack of efficient early diagnostics. Metastasis of the tumor being …

[HTML][HTML] Long non-coding RNAs as key regulators of cancer metastasis

P Koirala, DH Zou, YY Mo - Journal of Cancer Metastasis and …, 2016 - oaepublish.com
The recent advances in functional genomics have discovered that a large number of long
non-coding RNAs (lncRNAs) are pervasively transcribed from the human genome …

[HTML][HTML] Long noncoding RNAs in development and cancer: potential biomarkers and therapeutic targets

R Fatima, VS Akhade, D Pal, SMR Rao - Molecular and cellular therapies, 2015 - Springer
Long noncoding RNAs are emerging as key players in various fundamental biological
processes. We highlight the varied molecular mechanisms by which lncRNAs modulate …

[HTML][HTML] Long non-coding RNAs in cancer invasion and metastasis

X Shen, P Qi, X Du - Modern Pathology, 2015 - Elsevier
Recent large-scale transcriptome analyses have revealed that the human genome contains
more than just protein-coding genes. Indeed, a large number of transcripts, including long …

Insights into the roles of non-coding RNAs and angiogenesis in glioblastoma: An overview of current research and future perspectives

Z Song, Z Xue, Y Wang, M Imran, M Assiri… - Biochimica et Biophysica …, 2024 - Elsevier
Glioblastoma (GBM) is a highly aggressive type of primary brain cancer with a poor
prognosis, and despite intensive research, survival rates have not significantly improved …

Long non‐coding RNAs: How to regulate the metastasis of non–small‐cell lung cancer

C Fang, L Wang, C Gong, W Wu… - Journal of cellular and …, 2020 - Wiley Online Library
Non–small‐cell lung cancer (NSCLC) has become the most lethal human cancer because of
the high rate of metastasis. Hence, clarifying the molecular mechanism underlying NSCLC …

[图书][B] The long and short non-coding RNAs in cancer biology

E Song - 2016 - Springer
The studies on long and short noncoding RNAs (ncRNAs) brought mammalian gene
regulation into a new era, adding a complete new layer of cell signaling to the holistic gene …

[HTML][HTML] Roles of long noncoding RNAs in colorectal cancer metastasis

H Li, SQ Ma, J Huang, XP Chen, HH Zhou - Oncotarget, 2017 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the 3 rd most common malignancies worldwide. Metastasis is
responsible for more than 90% CRC patients' death. Long noncoding RNAs (lncRNAs) are …