Dihydromyricetin protects the liver via changes in lipid metabolism and enhanced ethanol metabolism
Background Excess alcohol (ethanol, EtOH) consumption is a significant cause of chronic
liver disease, accounting for nearly half of the cirrhosis‐associated deaths in the United …
liver disease, accounting for nearly half of the cirrhosis‐associated deaths in the United …
[HTML][HTML] Dihydromyricetin supplementation improves ethanol-induced lipid accumulation and inflammation
I Janilkarn-Urena, A Idrissova, M Zhang… - Frontiers in …, 2023 - frontiersin.org
Introduction Excessive alcohol consumption leads to a myriad of detrimental health effects,
including alcohol-associated liver disease (ALD). Unfortunately, no available treatments …
including alcohol-associated liver disease (ALD). Unfortunately, no available treatments …
Dihydromyricetin modulates p62 and autophagy crosstalk with the Keap-1/Nrf2 pathway to alleviate ethanol-induced hepatic injury
P Qiu, Y Dong, B Li, X Kang, C Gu, T Zhu, Y Luo… - Toxicology letters, 2017 - Elsevier
Increasing evidence has demonstrated that dihydromyricetin (DMY) contains highly effective
antioxidative, anti-inflammatory, anti-microbial and anti-diabetic properties. Nevertheless …
antioxidative, anti-inflammatory, anti-microbial and anti-diabetic properties. Nevertheless …
Dihydromyricetin improves mitochondrial outcomes in the liver of alcohol-fed mice via the AMPK/Sirt-1/PGC-1α signaling axis
Alcoholic liver disease (ALD), due to the multifactorial damage associated with alcohol
(ethanol) consumption and metabolism, is one of the most prevalent liver diseases in the …
(ethanol) consumption and metabolism, is one of the most prevalent liver diseases in the …
[HTML][HTML] Molecular mechanisms and therapeutic implications of dihydromyricetin in liver disease
J Chen, X Wang, T Xia, Y Bi, B Liu, J Fu… - Biomedicine & …, 2021 - Elsevier
Recent studies demonstrated that dihydromyricetin (DHM) has prominent therapeutic effects
on liver injury and liver cancer. By summarizing the current preclinical in vitro and in vivo …
on liver injury and liver cancer. By summarizing the current preclinical in vitro and in vivo …
Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration
S Dong, J Ji, L Hu, H Wang - Life sciences, 2019 - Elsevier
Aims We previously reported that Hovenia dulcis Thunb. extract, a traditional Chinese
medicine rich in dihydromyricetin (DHM), exhibited a significant hepatoprotective effect …
medicine rich in dihydromyricetin (DHM), exhibited a significant hepatoprotective effect …
Dihydromyricetin ameliorates oleic acid-induced lipid accumulation in L02 and HepG2 cells by inhibiting lipogenesis and oxidative stress
C Xie, Z Chen, C Zhang, X Xu, J Jin, W Zhan, T Han… - Life Sciences, 2016 - Elsevier
Aims Dihydromyricetin (DMY), a flavonoid component isolated from Ampelopsis
grossedentata, was recently reported to ameliorate nonalcoholic fatty liver disease (NAFLD) …
grossedentata, was recently reported to ameliorate nonalcoholic fatty liver disease (NAFLD) …
Modulation of SIRT1-mediated signaling cascades in the liver contributes to the amelioration of nonalcoholic steatohepatitis in high fat fed middle-aged LDL receptor …
Y Zeng, YQ Hua, W Wang, H Zhang, X Le Xu - Biochemical Pharmacology, 2020 - Elsevier
Dihydromyricetin (DMY) is the most abundant flavonoid in Ampelopsis grossedentata
possessing many pharmacological activities. But less is known about its protective effect …
possessing many pharmacological activities. But less is known about its protective effect …
Dihydromyricetin ameliorates nonalcoholic fatty liver disease by improving mitochondrial respiratory capacity and redox homeostasis through modulation of SIRT3 …
X Zeng, J Yang, O Hu, J Huang, L Ran… - Antioxidants & redox …, 2019 - liebertpub.com
Aims: Our previous clinical trial indicated that the flavonoid dihydromyricetin (DHM) could
improve hepatic steatosis in patients with nonalcoholic fatty liver disease (NAFLD), altough …
improve hepatic steatosis in patients with nonalcoholic fatty liver disease (NAFLD), altough …
[HTML][HTML] Myricetin modulates macrophage polarization and mitigates liver inflammation and fibrosis in a murine model of nonalcoholic steatohepatitis
This study aimed to investigate the beneficial effects of myricetin in a diet-induced
nonalcoholic steatohepatitis (NASH) model and the underlying mechanism. C57BL/6J mice …
nonalcoholic steatohepatitis (NASH) model and the underlying mechanism. C57BL/6J mice …
相关搜索
- changes in lipid metabolism
- oxidative stress lipid accumulation
- lipid homeostasis liver injury
- cell death liver injury
- regulation of transformation liver injury
- dihydromyricetin supplementation lipid accumulation
- sirt3 signaling liver disease
- redox homeostasis liver disease
- therapeutic implications liver disease
- molecular mechanisms liver disease