Stem cells: a potential treatment option for kidney diseases

D Liu, F Cheng, S Pan, Z Liu - Stem cell research & therapy, 2020 - Springer
… and differentiation, stem cell therapy opens new avenues for the development of renal
function and structural repair in kidney diseases. Mounting evidence suggests that stem cells

[HTML][HTML] A modular differentiation system maps multiple human kidney lineages from pluripotent stem cells

H Tsujimoto, T Kasahara, S Sueta, T Araoka… - Cell reports, 2020 - cell.com
… -like cells, which are subsequently differentiated into glomeruli, renal tubules, and collecting
ducts in vitro and further vascularized in vivo. Our selective differentiation protocols should …

Stem/progenitor cell in kidney: characteristics, homing, coordination, and maintenance

J Huang, Y Kong, C Xie, L Zhou - Stem Cell Research & Therapy, 2021 - Springer
stem cells in the bone marrow, owning the capacity to self-renew, proliferate, and differentiate
… We can distinguish their source because renal stem/progenitor cells in Bowman’s capsule …

Urine-derived stem cells: applications in regenerative and predictive medicine

G Bento, AK Shafigullina, AA Rizvanov, VA Sardão… - Cells, 2020 - mdpi.com
Renal differentiation of UDSC can be performed by cultivating cells in commercial kidney
differentiation medium [42]. Importantly, and as described above, transplanted UDSC do not …

Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients

A Fendler, D Bauer, J Busch, K Jung… - Nature …, 2020 - nature.com
… self-renewing cells and had a weaker effect on their differentiation during organoid formation,
or it had more moderate effects on these cells, permitting their differentiation before they …

Formation and optimization of three-dimensional organoids generated from urine-derived stem cells for renal function in vitro

G Sun, B Ding, M Wan, L Chen, J Jackson… - Stem cell research & …, 2020 - Springer
… of red blood cells are both frequently used as specific markers for renal characteristic and …
for renal cells, it can affect cell differentiation and contribute much to renal function in 3D …

[HTML][HTML] Reno-protection of urine-derived stem cells in a chronic kidney disease rat model induced by renal ischemia and nephrotoxicity

C Zhang, SK George, R Wu, PU Thakker… - … Journal of Biological …, 2020 - ncbi.nlm.nih.gov
… Urine derived stem cells (USC) are thought to originate from the parietal cells in renal
robust proliferative potential, multi-potential differentiation, and the ability to exert regenerative …

Extracellular vesicles from human liver stem cells inhibit renal cancer stem cell‐derived tumor growth in vitro and in vivo

A Brossa, V Fonsato, C Grange, S Tritta… - … Journal of Cancer, 2020 - Wiley Online Library
… To evaluate the possible activity of stem cell-derived EVs on differentiated tumor cells in
vivo, we isolated renal tumor cells from surgical specimens deriving from 17 RCC patients (…

The FGF, TGFβ and WNT axis Modulate Self-renewal of Human SIX2+ Urine Derived Renal Progenitor Cells

MS Rahman, W Wruck, LS Spitzhorn, L Nguyen… - Scientific reports, 2020 - nature.com
… protocols, the maturation state of the differentiated renal cells … We propose that using native
renal stem cells isolated … WNT induced differentiation of urine-derived renal progenitor cells- …

Mesenchymal stem cell-derived extracellular vesicles to the rescue of renal injury

L Birtwistle, XM Chen, C Pollock - International Journal of Molecular …, 2021 - mdpi.com
stem cell (MSC) therapies appear to show promise in regenerative medicine [4]. MSCs are
multipotent, non-haematopoietic stem cells, … replicate and differentiate into specialised cells to …