Toxicity risk assessment of pyriproxyfen and metabolites in the rat liver: A vitro study

H Liu, P Li, P Wang, D Liu, Z Zhou - Journal of hazardous materials, 2020 - Elsevier
… , assessing the metabolic behavior and toxic effects of PYR in mammals is the best means of
evaluating its risks to … PYR was dissolved in ethanol to a concentration of 50 mg/L. A 6.4 μL …

Ethanol exposure increases mutation rate through error-prone polymerases

K Voordeckers, C Colding, L Grasso, B Pardo… - Nature …, 2020 - nature.com
… effect of ethanol depends on its metabolism to acetaldehyde, we … metabolized by yeast
cells to formaldehyde, a known mutagen. Isopropanol on the other hand cannot be metabolized

Mode of action-based risk assessment of genotoxic carcinogens

A Hartwig, M Arand, B Epe, S Guth, G Jahnke… - Archives of …, 2020 - Springer
… been regarded as particularly relevant for risk assessment, with the assumption of the … ,
their metabolic precursors and DNA reactive metabolites are considered to represent risk

Risk assessment with gut microbiome and metabolite markers in NAFLD development

H Leung, X Long, Y Ni, L Qian, E Nychas… - Science translational …, 2022 - science.org
… For example, in the measurement of glucose metabolism, oral … Our metabolic signatures and
their taxonomic drivers … more than 140 g of ethanol/week for men or 70 g of ethanol/week for …

Microbiome-derived ethanol in nonalcoholic fatty liver disease

AS Meijnikman, M Davids, H Herrema, O Aydin… - Nature medicine, 2022 - nature.com
… , microbially produced ethanol could have the ability to alter lipid and glucose metabolism and
… Yet, reported peripheral blood concentrations of microbially derived ethanol are generally …

Fact versus fiction: a review of the evidence behind alcohol and antibiotic interactions

KA Mergenhagen, BA Wattengel… - Antimicrobial agents …, 2020 - Am Soc Microbiol
… activity or ethanol metabolism (73). No data No data … ethanol) and chronic alcohol exposure
(15% [vol/vol] ethanol for 60 days after 10 days of adaption with 5% and 10% [vol/vol] ethanol

… , productivity, fruit quality, and postharvest longevity through modifying nutrition, metabolism, and gene expression in tomato; potential benefits and risk assessment

M Neysanian, A Iranbakhsh, R Ahmadvand… - PloS one, 2020 - journals.plos.org
This study attempted to address molecular, developmental, and physiological responses of
tomato plants to foliar applications of selenium nanoparticles (nSe) at 0, 3, and 10 mgl -1 or …

Acetate reprograms gut microbiota during alcohol consumption

C Martino, LS Zaramela, B Gao, M Embree… - Nature …, 2022 - nature.com
… Our results show that ethanol is not directly metabolized by the gut microbiota, … ethanol
metabolism and trace the fate of ethanol, we administered stable isotope labeled [1- 13 C] ethanol

Non-alcoholic fatty liver disease: metabolic, genetic, epigenetic and environmental risk factors

O Juanola, S Martínez-López, R Francés… - International journal of …, 2021 - mdpi.com
… such as excessive alcohol consumption (<20 g ethanol/day), viral or autoimmune hepatitis,
… about the metabolic dysfunction associated with the disease. “MAFLD”, metabolic associated …

Organoarsenicals in seafood: occurrence, dietary exposure, toxicity, and risk assessment considerations–A review

C Luvonga, CA Rimmer, LL Yu… - Journal of agricultural and …, 2020 - ACS Publications
… On the basis of projected exposure level and expected metabolism, it … metabolic intermediates
from in vitro assessment confirms the necessity for animal and human research to assess