Key steps for effective breast cancer prevention

KL Britt, J Cuzick, KA Phillips - Nature Reviews Cancer, 2020 - nature.com
risk and targeting them for specific interventions, such as risk-… ’s breast cancer risk using
validated risk assessment models, … inclusion of newer risk factors, such as polygenic risk and …

[HTML][HTML] Unraveling the complex interplay between epigenetics and immunity in alcohol-associated liver disease: A comprehensive review

Y Liu, T Liu, F Zhang, Y Gao - International Journal of Biological …, 2023 - ncbi.nlm.nih.gov
… This site-specific acetylation was attenuated by the inhibition of ethanol metabolism by … not
enhanced by chronic ethanol treatment. These findings suggest that ethanol may induce the …

Identification of energy metabolism genes for the prediction of survival in hepatocellular carcinoma

Q Chen, F Li, Y Gao, G Xu, L Liang, J Xu - Frontiers in oncology, 2020 - frontiersin.org
… The risk score calculated from the established risk model in 204 samples and other clinical
… energy metabolism-related molecular subtypes with different prognosis. Then, a risk model …

Impact of drinking alcohol on gut microbiota: Recent perspectives on ethanol and alcoholic beverage

E Lee, JE Lee - Current opinion in food science, 2021 - Elsevier
… Alcohol is absorbed in the gastrointestinal tract (GIT), transferred to the liver and lungs
where it is metabolized. In this process, ethanol and its metabolites cause health complications …

Multi-omic studies on the toxicity variations in effluents from different units of reclaimed water treatment

Y Deng, Y Zhang, H Ren - Water Research, 2022 - Elsevier
… and induced abnormal lipid metabolism and immune response. … Our results strongly highlight
that the health risks of reclaimed … correlated with serum ethanol and taurine, respectively. …

Assessment of hypolipidemic and anti‐inflammatory properties of walnut (Juglans regia) seed coat extract and modulates some metabolic enzymes activity in triton …

E Palabıyık, AN Sulumer, H Uguz, B Avcı… - Journal of Molecular …, 2023 - Wiley Online Library
… of ethanol extract walnut (Juglans regia) seed coat (E-WSC) on some metabolic enzymes
(… alterations in the activity of the investigated metabolic enzymes were prevented by E-WSC. …

Alcohol-induced oxidative stress and the role of antioxidants in alcohol use disorder: a systematic review

EE Tsermpini, A Plemenitaš Ilješ, V Dolžan - Antioxidants, 2022 - mdpi.com
… Haorah and colleagues hypothesized and indicated that the generation of ROS and NO in
human neurons during ethanol metabolism by ADH and CYP2E1 is due to the activation of …

[HTML][HTML] Current understanding of the metabolism of micronutrients in chronic alcoholic liver disease

J Wu, QH Meng - World Journal of Gastroenterology, 2020 - ncbi.nlm.nih.gov
… Iron metabolic disorder may induce irreversible damage to cellular homeostasis. There is
a … Actually, ethanol by itself can directly induce ferritin synthesis and suppress IL-6-mediated …

Alcohol and breast cancer

B Starek-Świechowicz, B Budziszewska… - Pharmacological …, 2023 - Springer
… This paper discusses both ethanol metabolism and the mechanisms of mammary
tumourigenesis caused by alcohol. Numerous signalling pathways in neoplastic transformation …

Dihydromyricetin improves mitochondrial outcomes in the liver of alcohol-fed mice via the AMPK/Sirt-1/PGC-1α signaling axis

J Silva, MH Spatz, C Folk, A Chang, E Cadenas… - Alcohol, 2021 - Elsevier
… As part of this later effort, we found that DHM enhances ethanol metabolism in the liver, in
part due to increased NAD + concentrations. Moreover, we found that DHM can reduce hepatic …