[HTML][HTML] Distinct contributions of metabolic dysfunction and genetic risk factors in the pathogenesis of non-alcoholic fatty liver disease

PK Luukkonen, S Qadri, N Ahlholm, K Porthan… - Journal of …, 2022 - Elsevier
risk, defined by the number of risk alleles in PNPLA3, TM6SF2, MBOAT7, HSD17B13 and
MARC1, increase the features of NAFLD independently of each other and other known risk

Proinflammatory properties and lipid disturbance of polystyrene microplastics in the livers of mice with acute colitis

H Zheng, J Wang, X Wei, L Chang, S Liu - Science of the Total Environment, 2021 - Elsevier
… dehydrated with different concentrations of ethanol. Ethanol from low concentration to high
… induced greater disturbance of energy metabolism and lipid metabolism. In summary, PS …

Environmental exposure during pregnancy: influence on prenatal development and early life: a comprehensive review

MD Gómez-Roig, R Pascal, MJ Cahuana… - Fetal diagnosis and …, 2021 - karger.com
… Alcohol affects multiple metabolic pathways during foetal development, partly through the
alteration … Moreover, ethanol metabolism increases the production of reactive oxygen species, …

Transformed ALDH2−/− hepatocytes by ethanol could serve as a useful tool for studying alcoholic hepatocarcinogenesis

XN Zhang, FG Meng, YR Wang, SX Liu, T Zeng - Medical Hypotheses, 2021 - Elsevier
Ethanol is metabolized to genotoxic acetaldehyde by cytosolic alcohol dehydrogenase (ADH)
and microsomal cytochrome P4502E1 (CYP2E1), and acetaldehyde is then metabolized

Type-dependent effects of microplastics on tomato (Lycopersicon esculentum L.): Focus on root exudates and metabolic reprogramming

R Shi, W Liu, Y Lian, A Zeb, Q Wang - Science of The Total Environment, 2023 - Elsevier
… acid metabolism. We also found that plants exposed to PS and PP MPs produced more
significant metabolic … on the toxic effect of various MPs on crops and their future risk assessment. …

The pathophysiological role of CoA

A Czumaj, S Szrok-Jurga, A Hebanowska… - International Journal of …, 2020 - mdpi.com
… The importance of coenzyme A (CoA) as a carrier of acyl residues in cell metabolism is well
… those involved in the metabolism of lipids, carbohydrates, proteins, ethanol, bile acids, and …

[HTML][HTML] Puerariae Lobatae radix flavonoids and puerarin alleviate alcoholic liver injury in zebrafish by regulating alcohol and lipid metabolism

YS Liu, MH Yuan, CY Zhang, HM Liu, JR Liu… - Biomedicine & …, 2021 - Elsevier
… the metabolism of ethanol in zebrafish livers. CYP2y3 can accelerate the accumulation of
ethanol … In addition, CYP3a65 plays a critical role in the metabolism of substances. In brief, the …

Human health risk assessment of bisphenol A (BPA) through meat products

X Wang, R Nag, NP Brunton, MAB Siddique… - Environmental …, 2022 - Elsevier
… Then, the metabolic pathway of glucuronidation happens in the liver. Glucuronidation is the
primary pathway of BPA metabolism and detoxification in the human body. BPA glucuronide (…

Impact of alcohol consumption on male fertility potential: a narrative review

R Finelli, F Mottola, A Agarwal - International Journal of Environmental …, 2021 - mdpi.com
… This narrative review summarizes the impact of excessive alcohol consumption on male
fertility by describing its metabolism and how ethanol consumption may induce cellular damage. …

Plant‐based foods and their bioactive compounds on fatty liver disease: Effects, mechanisms, and clinical application

HY Li, RY Gan, A Shang, QQ Mao… - Oxidative medicine …, 2021 - Wiley Online Library
ethanol metabolism. More importantly, clinical trials confirmed the beneficial effects of
plant-based foods on patients with fatty liver. However, several issues need to be further studied …