Involvement of inflammation and its resolution in disease and therapeutics

S Alfaro, V Acuña, R Ceriani, MF Cavieres… - International Journal of …, 2022 - mdpi.com
… with unlimited inflammation. In this review, we have described the role of inflammation in
the acute and chronic response to pathogen infection and the inflammatory reaction to …

[HTML][HTML] Inflammation and cardiovascular disease: From mechanisms to therapeutics

A Alfaddagh, SS Martin, TM Leucker, ED Michos… - American journal of …, 2020 - Elsevier
inflammatory response. Herein we provide an overview of the role of inflammation in
atherosclerotic cardiovascular disease… various biomarkers involved in inflammation, and …

The role of inflammation in cardiovascular disease

MY Henein, S Vancheri, G Longo… - International journal of …, 2022 - mdpi.com
… is a chronic inflammatory disease, in which the immune system has a prominent role in its …
This review summarizes the current knowledge about the role of inflammation and the immune …

The role of P-selectin in cancer-associated thrombosis and beyond

E Yeini, R Satchi-Fainaro - Thrombosis research, 2022 - Elsevier
… As we discuss the different roles of SELP in cancer progression and disease course, the
use of SELP-targeted therapies may lead to improved therapeutic outcome. However, since …

Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease

L Liberale, F Montecucco, JC Tardif… - European heart …, 2020 - academic.oup.com
Inflammation has recently emerged as an important contributor for CV disease development.
Indeed, a state of chronic sterile low-grade inflammation characterizes older organisms (…

Selectins impair regulatory T cell function and contribute to systemic lupus erythematosus pathogenesis

M Scherlinger, V Guillotin, I Douchet… - Science Translational …, 2021 - science.org
… In a mouse model of SLE, P-selectin blockade attenuated disease severity. Collectively, our
… evidence of the role of P-selectin in SLE pathogenesis and point to P-selectin as a valuable …

Plasma P-selectin level is associated with severity of coronary heart disease in Chinese Han population

C Song, G Wu, S Chang, L Bie - Journal of International …, 2020 - journals.sagepub.com
selectin levels and the severity of coronary heart disease (CHD) in a Chinese Han population.
… These results will further our understanding of the role of P-selectin in CHD in the Chinese …

Selectins—the two Dr. Jekyll and Mr. Hyde faces of adhesion molecules—a review

I Tvaroška, C Selvaraj, J Koča - Molecules, 2020 - mdpi.com
selectins and their ligands as therapeutic targets in chronic and acute inflammatory diseases
… We will emphasize the structural characteristic of selectins and the catalytic mechanisms of …

Selectin-mediated signaling—Shedding light on the regulation of integrin activity in neutrophils

A Cappenberg, M Kardell, A Zarbock - Cells, 2022 - mdpi.com
… In conclusion, β 2 -integrins and selectins have been shown to play a crucial role in
different human inflammatory diseases and are, therefore, potential targets for therapeutic …

[PDF][PDF] The Role of L-selectin in Tuberculosis and HIV Coinfection: Implications for Disease Diagnosis and Management

EI Obeagu, GU Obeagu - Elite Journal of Public Health, 2024 - researchgate.net
… , influencing disease pathogenesis and clinical outcomes. This review examines the role
of L-selectin in TB and HIV coinfection, focusing on its implications for disease diagnosis and …