Beyond restriction modification: epigenomic roles of DNA methylation in prokaryotes

BP Anton, RJ Roberts - Annual Review of Microbiology, 2021 - annualreviews.org
… , DNA methylation is an epigenetic signal capable of altering the interpretation of genetic
information without change to the DNA sequence itself. … far less sequence conservation than the …

[HTML][HTML] A comparative methylome analysis reveals conservation and divergence of DNA methylation patterns and functions in vertebrates

H Al Adhami, AF Bardet, M Dumas, E Cleroux… - BMC biology, 2022 - Springer
… We analyze the evolutionary conservation of DNA methylation … of DNA methylation in
vertebrate cells by DNA methylation … CG-rich sequences are more frequently methylated in germ …

[HTML][HTML] Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods

SH Lewis, L Ross, SA Bain, E Pahita, SA Smith… - PLoS …, 2020 - journals.plos.org
… on a genome-wide scale, we carried out whole-genome bisulphite sequencing. We used
the DNeasy Blood and Tissue kit (QIAGEN) according to the manufacturer’s protocol to extract …

A Bayesian hierarchical model to estimate DNA methylation conservation in colorectal tumors

KA Murgas, Y Ma, LK Shahidi, S Mukherjee… - …, 2022 - academic.oup.com
… The resulting bisulfite-converted product is hybridized to paired fluorescent red/green probes
specific for the DNA sequence around a single CpG site, with the color corresponding to …

[HTML][HTML] DNA methylation clocks for clawed frogs reveal evolutionary conservation of epigenetic aging

JA Zoller, E Parasyraki, AT Lu, A Haghani, C Niehrs… - GeroScience, 2024 - Springer
… To ask, if we can establish epigenetic DNA methylation clocks for Xenopus, we first established
a method to quantify genomic DNA methylation at sufficient sequencing depth. We used …

[HTML][HTML] A mammalian methylation array for profiling methylation levels at conserved sequences

A Arneson, A Haghani, MJ Thompson… - Nature …, 2022 - nature.com
DNA methylation levels for fractional methylation called from whole-genome bisulfite sequencing
… in highly conserved stretches of DNA based on sequence conservation, we assessed …

[HTML][HTML] Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species

J Klughammer, D Romanovskaia, A Nemc… - Nature …, 2023 - nature.com
DNA methylation and the underlying DNA sequence … -specific DNA methylation levels based
on the DNA sequence of … degree of conservation in the characteristics of DNA methylation

Conserved DNA methyltransferases: a window into fundamental mechanisms of epigenetic regulation in bacteria

PH Oliveira, G Fang - Trends in microbiology, 2021 - cell.com
sequence. Instead, significant meaning can also be conveyed through the epigenetic states
of DNA (eg, by chemical modification such as DNA methylation)… of DNA MTase conservation

[PDF][PDF] Genome-wide DNA methylation differences between conservation and breeding populations of Shaoxing ducks

L Xu, Z Shi, H Li, J He, B Chen, Z Tao, Y Tian, L Chen… - Heliyon, 2022 - cell.com
… -wide DNA methylation detection technique was used to analyze the differential methylation
in … The methylation density of different sequences differed among the three groups, and the …

[HTML][HTML] Analysis of genome and methylation changes in Chinese indigenous chickens over time provides insight into species conservation

T Zeng, J Yin, P Feng, F Han, Y Tian, Y Wang… - Communications …, 2022 - nature.com
DNA methylation variations during different conservation programmes, and hold practical
relevance for species conservation. … performed whole-genome sequence analysis and WGBS …