[HTML][HTML] p38 MAPKs—roles in skeletal muscle physiology, disease mechanisms, and as potential therapeutic targets

CM Brennan, CP Emerson Jr, J Owens, N Christoforou - JCI insight, 2021 - ncbi.nlm.nih.gov
… Here, we explore the role of p38 in regulating skeletal muscle homeostasis, the disease
process, and p38α/β targeting as an approach to treating muscular dystrophies, such as …

Myokines in skeletal muscle physiology and metabolism: Recent advances and future perspectives

DK Das, ZA Graham, CP Cardozo - Acta Physiologica, 2020 - Wiley Online Library
… associated with traits related to skeletal muscle physiology and metabolism, with multiple …
studies have examined relationships between SNPs and muscle strength in GWAS studies. …

Skeletal muscle: A review of molecular structure and function, in health and disease

K Mukund, S Subramaniam - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
… Decades of research in skeletal muscle physiology have provided multiscale insights into
the … Skeletal muscle can be viewed as a biomechanical device with various interacting …

The role of oxidative stress in skeletal muscle myogenesis and muscle disease

D Lian, MM Chen, H Wu, S Deng, X Hu - Antioxidants, 2022 - mdpi.com
skeletal muscle physiology and pathology. In this review, we summarize the sources of
reactive oxygen species in skeletal muscle … the effects of ROS on skeletal muscle, describe the …

Physiological and molecular sex differences in human skeletal muscle in response to exercise training

S Landen, D Hiam, S Voisin, M Jacques… - … of physiology, 2023 - Wiley Online Library
… study (Gender affirming hormone therapy on skeletal muscle training and epigenetics), which
aims to elucidate the effect of hormone therapy by integrating skeletal muscle -omic layers. …

Skeletal muscle extracellular matrix–what do we know about its composition, regulation, and physiological roles? A narrative review

R Csapo, M Gumpenberger, B Wessner - Frontiers in physiology, 2020 - frontiersin.org
… components of skeletal muscles, we provide an overview over the current state of knowledge
concerning the composition, structure and regulation of the ECM, its physiological roles, …

Fiber-type traps: revisiting common misconceptions about skeletal muscle fiber types with application to motor control, biomechanics, physiology, and biology

SS Blemker, SV Brooks, KA Esser… - … of Applied Physiology, 2024 - journals.physiology.org
… Many decades of careful 492 research have formed the basis for our modern and advanced
understanding of muscle physiology. However, as 493 the muscle physiology field has …

Loss of mitochondrial Ca2+ uptake protein 3 impairs skeletal muscle calcium handling and exercise capacity

B Roman, Y Mastoor, Y Zhang, D Gross… - … of Physiology, 2024 - Wiley Online Library
… The data in this study provide evidence suggesting that MICU3 plays an important role in
skeletal muscle physiology. MICU3-KO mice are healthy and do not exhibit any adverse …

Tissue-engineered skeletal muscle models to study muscle function, plasticity, and disease

A Khodabukus - Frontiers in Physiology, 2021 - frontiersin.org
… First, we discuss the generation and function of in vitro skeletal muscle models. We then …
skeletal muscle fiber-type in vivo and the ability of current in vitro models to study muscle fiber-…

Roles of estrogen, estrogen receptors, and estrogen-related receptors in skeletal muscle: regulation of mitochondrial function

K Yoh, K Ikeda, K Horie, S Inoue - International journal of molecular …, 2023 - mdpi.com
skeletal muscles, such as muscle mass maintenance, muscle exercise physiology, and muscle
… In this article, we review potential regulatory roles of ERs and ERRs in muscle physiology