Erlotinib

AA Abdelgalil, HM Al-Kahtani, FI Al-Jenoobi - Profiles of Drug Substances …, 2020 - Elsevier
Erlotinib inhibited epidermal growth factor receptor (EGFR) … This study presents a
comprehensive profile of erlotinib, … methods of analysis (including spectroscopic, electrochemical, …

[HTML][HTML] … inhibitor erlotinib with a model transport protein in the presence of quercetin: A drug–protein and drugdrug interaction investigation using multi-spectroscopic …

TA Wani, MM Alanazi, NA Alsaif, AH Bakheit, S Zargar… - Molecules, 2022 - mdpi.com
… Therefore, various spectroscopic experiments were conducted in addition to in silico studies
to evaluate the interaction behavior of the BSA-ERL system in the presence and absence of …

Probing the combination of erlotinib hydrochloride, an anticancer drug, and human serum albumin: Spectroscopic, molecular docking, and molecular dynamic …

S Shahraki, Z Razmara, HS Delarami… - …, 2023 - Wiley Online Library
Studying the interaction of drugs with important biological molecules such as proteins and …
HSA and Erlotinib hydrochloride (Erlo) has been studied using multispectroscopic, molecular …

Density functional methods study on the structures and spectral characteristics for pharmacophoric conformers, metabolites, and combined fragments of Erlotinib

YY Weng, X Sun, LX Wang, YY Liao, CJ Wang - Chemical Papers, 2022 - Springer
… According to the energetics and spectroscopic characteristics, either the Erlotinib itself or
its complexes and metabolites in conformation A or B could be distinguished in aqueous …

A physicochemical and spectroscopic characterization of novel erlotinib conjugates with platinum nanoparticles

P Gnacek, N Piergies, D Duraczyńska, M Kozak… - Colloids and Surfaces A …, 2022 - Elsevier
… These spectroscopic studies revealed that the chemisorption of MTX onto the AgNP surface
occurs thorough a carboxylic group and via the exchange with a citrate molecules. However, …

[HTML][HTML] Spectroscopic insights into the effect of pH, temperature, and stabilizer on erlotinib adsorption behavior onto Ag nanosurface

N Piergies, M Oćwieja, C Paluszkiewicz… - … Spectroscopy, 2020 - Elsevier
studies, the surface - enhanced Raman spectroscopy (SERS) is applied for the first time in
order to describe erlotinib/… The broad spectroscopic studies of the erlotinib/AgNP conjugates …

Validated UV spectrophotometric methods for the determination of anticancer drug erlotinib hydrochloride in bulk and tablet formulations

RD Rathod, LD Rathod, AB Mundada… - … of Applied Spectroscopy, 2021 - Springer
… Linearity studies. For the linearity study, solutions of erlotinib hydrochloride of different …
The powder drug equivalent to 10 mg of erlotinib hydrochloride was transferred into a 100-…

Polymorphism in Erlotinib Hydrochloride: New Insights into Relative Stability, Thermal Behavior, and Structural Differences of Forms A and B

CT António, AOL Évora, CES Bernardes… - Crystal Growth & …, 2023 - ACS Publications
Erlotinib hydrochloride (EtbHCl), whose polymorphism is still ill-characterized, is an essential
component of the current armamentarium for the treatment of pancreatic and lung cancers. …

Antioxidant activity of erlotinib and gefitinib: theoretical and experimental insights

SH K. P, TD Babu, P C. M, G Joshy… - Free Radical …, 2022 - Taylor & Francis
… has not been studied thus far. In this study, the antioxidant activity of erlotinib and gefitinib
was … UV–visible spectroscopy revealed the possible electronic transitions between the FMOs …

Development and Validation of the Ultraviolet Spectrophotometric Method for Determination of Erlotinib Hydrochloride

RA Jadav, MA Ambasana, AH Bapodra - Journal of Applied Spectroscopy, 2022 - Springer
Erlotinib hydrochloride has been used to … Erlotinib exhibited a survival benefit in lung
cancer in phase III trials. The US Food and Drug Administration has approved the use of erlotinib