Down syndrome

SE Antonarakis, BG Skotko, MS Rafii… - Nature Reviews …, 2020 - nature.com
Down syndrome (DS) is the most common genomic disorder of intellectual disability and is …
of the syndrome is from Down, who described the clinical aspects of the syndrome in 1866 (ref…

Children with Down syndrome can benefit from language interventions; Results from a systematic review and meta-analysis

E Smith, S Hokstad, KAB Næss - Journal of Communication Disorders, 2020 - Elsevier
… for children with Down syndrome to reveal knowledge about the … relevant for education,
speech and language therapy, and … skills in children with Down syndrome. Overall, there was a …

Vowel acoustics and speech intelligibility in young adults with Down syndrome

M Carl, RD Kent, ES Levy, DH Whalen - … of Speech, Language, and Hearing …, 2020 - ASHA
Speech production deficits and reduced intelligibility are frequently noted in individuals with
Down syndrome (… and relates these findings to perceptual analysis of speech intelligibility. …

Opportunities, barriers, and recommendations in Down syndrome research

…, A Amon, L Abbeduto, S Agiovlasitis… - … science of rare …, 2020 - content.iospress.com
… Studies that can distinguish the effects of motor speech disorders from effects caused by
anatomical dysmorphology are needed to develop tools for clinical assessments and to facilitate …

Feeding problems and gastrointestinal diseases in Down syndrome

A Ravel, C Mircher, AS Rebillat, C Cieuta-Walti… - Archives de …, 2020 - Elsevier
… gastrointestinal disorders are the most common anomalies in people with Down syndrome
(… Frequent chewing disorders and aspiration are cause for early speech therapy rehabilitation…

Neurologic complications of Down syndrome: a systematic review

JD Santoro, D Pagarkar, DT Chu, M Rosso… - Journal of …, 2021 - Springer
… All MeSH terms searched included the term “Down syndrome.” MeSH search terms are
detailed in Appendix A. Of note, utilization of the MeSH term Down syndrome also included 13 …

Down syndrome

KC Chan, AM Li - … Medicine: Mechanisms and Comprehensive Guide to …, 2021 - Springer
Down syndrome (DS) is the most common chromosomal abnormality, and the usual quoted
annual incidence is 1 in 700–800 live births worldwide. Sleep problems, and especially …

A meta-analysis of prosody in autism, Williams syndrome, and Down syndrome

SJ Loveall, K Hawthorne, M Gaines - Journal of Communication Disorders, 2021 - Elsevier
… Prosody, the rhythm and melody of speech, plays a significant role in an individual’s ability …
autism spectrum disorders (ASD), Williams syndrome (WS), and Down syndrome (DS). These …

The importance of deep speech phenotyping for neurodevelopmental and genetic disorders: A conceptual review

KV Chenausky, H Tager-Flusberg - … of Neurodevelopmental Disorders, 2022 - Springer
… NDDs such as cerebral palsy or Down syndrome (DS) may be associated with different
types of dysarthria (eg, flaccid and/or ataxic) at the same time or at different points in …

Multiorgan involvement and management in children with Down syndrome

N Lagan, D Huggard, F Mc Grane, TR Leahy… - Acta …, 2020 - Wiley Online Library
… An increased prevalence with Moya-Moya syndrome in individuals with Down syndrome has
been noted of up to 26-fold.43 Moya-Moya is a chronic, occlusive, cerebrovascular disorder