YAP contributes to DNA methylation remodeling upon mouse embryonic stem cell differentiation

F Passaro, I De Martino, F Zambelli… - Journal of Biological …, 2021 - ASBMB
… the methylation pattern of CTR and YAP KD cell in undifferentiated ESCs (T0) versus cells
differentiated … the changes in genomic DNA methylation occurring in CTR cells upon 4 days of …

Arabidopsis shoot stem cells display dynamic transcription and DNA methylation patterns

R Gutzat, K Rembart, T Nussbaumer, F Hofmann… - The EMBO …, 2020 - embopress.org
… genomes indicates resetting of transposon silencing and early germ cell differentiation. …
control for DNA methylation in stem cells at the transition to the next generation, and several cell

Analysis of the epigenetic signature of cell reprogramming by computational DNA methylation profiles

Y Zuo, M Song, H Li, X Chen, P Cao… - Current …, 2020 - ingentaconnect.com
… ) cells. The heterogeneity of iPS has a greater deviation in the DNA hypermethylation pattern.
… of stem cells, and nine genes of cell differentiation were identified (Fig. 5A and Fig. S8A). …

DNA methylation disruption reshapes the hematopoietic differentiation landscape

F Izzo, SC Lee, A Poran, R Chaligne, F Gaiti, B Gross… - Nature …, 2020 - nature.com
… to transcriptional priming skews in uncommitted hematopoietic stem cells. To reconcile
genome-… differentiation, and that lack of Tet1 or Tet2 expression impairs B-cell differentiation by …

[HTML][HTML] DNA methylation patterning and the regulation of beta cell homeostasis

N Parveen, S Dhawan - Frontiers in Endocrinology, 2021 - frontiersin.org
… in utilizing beta cell specific DNA methylation patterns for the … to determine the differentiation
status of stem cell derived … , and stem-cell models of beta cell differentiation have been …

Understanding the relevance of DNA methylation changes in immune differentiation and disease

C Calle-Fabregat, O Morante-Palacios, E Ballestar - Genes, 2020 - mdpi.com
… hematopoietic stem cells (HSCs), which are the only cell type … Since the establishment of
correct DNA methylation patterns … regulation of B cell differentiation by epigenetic mechanisms, …

DNA methylation changes during long-term in vitro cell culture are caused by epigenetic drift

J Franzen, T Georgomanolis, A Selich, CC Kuo… - Communications …, 2021 - nature.com
… a Mesenchymal stem cells from umbilical cord were labeled with barcoded-RGB-vectors
to correlate DNAm patterns with the composition of cellular subsets 30 . Deep sequencing …

[PDF][PDF] Large DNA methylation nadirs anchor chromatin loops maintaining hematopoietic stem cell identity

X Zhang, M Jeong, X Huang, XQ Wang, X Wang… - Molecular cell, 2020 - cell.com
… The DNA methylation patterns are maintained by competing … in stem and progenitor cells,
diminishing as cells differentiate. … and illuminate the role of DNA methylation in the genome. …

[HTML][HTML] DNA methylation in epidermal differentiation, aging, and cancer

F Köhler, M Rodríguez-Paredes - Journal of Investigative Dermatology, 2020 - Elsevier
… previously implicated in hair follicle stem cell functions, like Sox9, … that adult stem cell
differentiation causes a general methylation … In this work, DNA methylation patterns of old …

PRDM8 reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation

O Cypris, M Eipel, J Franzen, C Rösseler… - Clinical …, 2020 - Springer
… of this gene in induced pluripotent stem cells (iPSCs), we created … We then analyzed the
DNA methylation patterns within … during cellular differentiation or in specific cellular subsets. …