Epigenetic alterations under oxidative stress in stem cells

M Huang, Q Wu, ZH Jiang - Oxidative Medicine and Cellular …, 2022 - Wiley Online Library
… findings on the oxidative effects on DNA and histone modifications in stem cells. We
propose that epigenetic alterations and oxidative stress may influence each other in stem cells. …

The secretome of mesenchymal stem cells and oxidative stress: challenges and opportunities in cell-free regenerative medicine

B Rahimi, M Panahi, N Saraygord-Afshari… - Molecular Biology …, 2021 - Springer
… activity of stem cells, there is some evidence about the protective effects of cytokines on
oxidative … (IGF) protects intestinal epithelial cells and fibroblasts against oxidative conditions, the …

Mesenchymal stem cell-derived small extracellular vesicles mitigate oxidative stress-induced senescence in endothelial cells via regulation of miR-146a/Src

X Xiao, M Xu, H Yu, L Wang, X Li, J Rak… - Signal transduction and …, 2021 - nature.com
… We intended to investigate the effect of MSC-sEV on oxidative stress-induced HUVECs
senescence … agent via miR-146/Src pathway to prevent oxidative stress-induced EC senescence. …

Exosomes from adipose-derived stem cells alleviate the inflammation and oxidative stress via regulating Nrf2/HO-1 axis in macrophages

K Shen, Y Jia, X Wang, J Zhang, K Liu, J Wang… - Free Radical Biology …, 2021 - Elsevier
oxidative stress-induced skin injury by alleviating cellular and histological responses to
inflammation and oxidation … Increasing studies revealed that stem cell exosomes could regulate …

Oxidative stress, inflammation, and autophagy: potential targets of mesenchymal stem cells-based therapies in ischemic stroke

J He, J Liu, Y Huang, X Tang, H Xiao… - Frontiers in Neuroscience, 2021 - frontiersin.org
… that oxidative stress, neuroinflammation, and autophagy dysfunction worked together to
damage cells … among oxidative stress, inflammatory activity, and autophagy in ischemic stroke. …

Conditioned medium from bone marrow mesenchymal stem cells restored oxidative stress-related impaired osteogenic differentiation

R Saleem, S Mohamed-Ahmed, R Elnour… - International Journal of …, 2021 - mdpi.com
Oxidative stress from high levels of intracellular reactive … Previous studies indicate that
mesenchymal stem cells (MSC) … mesenchymal stem cells (hBMSC) exposed to oxidative stress

GSH-AuNP anti-oxidative stress, ER stress and mitochondrial dysfunction in amyloid-beta peptide-treated human neural stem cells

MC Chiang, CJB Nicol - Free Radical Biology and Medicine, 2022 - Elsevier
… promote oxidative stress, endoplasmic reticulum (ER) stress and … the viability of human neural
stem cells (hNSCs) with Aβ, … protected from Aβ-induced oxidative stress, as detected using …

The effect of photobiomodulation therapy on antioxidants and oxidative stress profiles of adipose derived mesenchymal stem cells in diabetic rats

A Mostafavinia, H Ahmadi, A Amini… - … Acta Part A: Molecular …, 2021 - Elsevier
We studied the effects of photobiomodulation therapy (PBMT) on adipose-derived mesenchymal
stem cells (ADSCs) which were extracted from streptozotocin (STZ) induced diabetic …

ADGRG1 enriches for functional human hematopoietic stem cells following ex vivo expansion–induced mitochondrial oxidative stress

Y Chen, S Fang, Q Ding, R Jiang, J He… - The Journal of …, 2021 - Am Soc Clin Investig
… Using single-cell RNA-Seq analysis of the mitoROS low cell … + CD133 + CB cells upon ex
vivo expansion stress. Gene set … functional human HSCs under oxidative stress during ex vivo …

Leonurine protects bone mesenchymal stem cells from oxidative stress by activating mitophagy through PI3K/Akt/mTOR pathway

B Zhao, Q Peng, D Wang, R Zhou, R Wang, Y Zhu, S Qi - Cells, 2022 - mdpi.com
… to oxidative stress. The function of leonurine on bone marrow-derived mesenchymal stem
cells (BMSCs) under oxidative stress … We found that leonurine can alleviate cell apoptosis and …