Human umbilical cord-derived mesenchymal stem cells prevent the progression of early diabetic nephropathy through inhibiting inflammation and fibrosis

E Xiang, B Han, Q Zhang, W Rao, Z Wang… - Stem cell research & …, 2020 - Springer
… Risk factors for DN include advanced age, gender, long disease course, obesity, high salt
diet, dyslipidemia, nephrotoxic substances, acute kidney injury, and excessive protein intake. …

The Renoprotective and Anti-Inflammatory Effects of Human Urine-Derived Stem Cells on Acute Kidney Injury Animals.

Y Kuang, C Fan, X Long, J Zheng, Y Zeng… - Current Stem Cell …, 2024 - europepmc.org
Background Acute Kidney Injury (AKI) is defined as a sudden loss of kidney function, which
is often caused by drugs, toxins, and infections. The large spectrum of AKI implies diverse …

Targeting acute kidney injury in COVID-19

JA Kellum, JWO van Till… - Nephrology Dialysis …, 2020 - academic.oup.com
… However, in a follow-up report, the extent of kidney injury was seen to be much larger as
24% of all COVID-19 ICU patients required renal support (May 8 report; n = 8250), which was …

Protective effect of miRNA-containing extracellular vesicles derived from mesenchymal stromal cells of old rats on renal function in chronic kidney disease

Y Wang, YF Guo, GP Fu, C Guan, X Zhang… - Stem cell research & …, 2020 - Springer
… Extracellular vesicles (EVs) released from MSCs contribute to the repair of kidney injury. We
explored the influence of senescence on EVs derived from MSCs (MSC-EVs) and detected …

Metformin inhibits chronic kidney disease‐induced DNA damage and senescence of mesenchymal stem cells

H Kim, MR Yu, H Lee, SH Kwon, JS Jeon, DC Han… - Aging cell, 2021 - Wiley Online Library
Mesenchymal stem cells (MSCs) are promising source of cell‐based regenerative therapy.
In consideration of the risk of allosensitization, autologous MSC‐based therapy is preferred …

Mesenchymal stem cell-derived extracellular vesicles attenuate mitochondrial damage and inflammation by stabilizing mitochondrial DNA

M Zhao, S Liu, C Wang, Y Wang, M Wan, F Liu… - ACS …, 2020 - ACS Publications
… the tissue regenerative role of mesenchymal stem cell (MSC)-… cells remains elusive. Here,
we report that MSC-EVs attenuated mtDNA damage and inflammation after acute kidney injury

Mesenchymal stem cells exert renoprotection via extracellular vesicle-mediated modulation of M2 macrophages and spleen-kidney network

Y Shimamura, K Furuhashi, A Tanaka… - Communications …, 2022 - nature.com
… the renoprotective effect and Treg induction by ASCs, indicating that the interaction of ASCs
with immune cells in the spleen is essential for the therapeutic effects against kidney injury. …

[HTML][HTML] Quercetin alleviates acute kidney injury by inhibiting ferroptosis

Y Wang, F Quan, Q Cao, Y Lin, C Yue, R Bi… - Journal of advanced …, 2021 - Elsevier
… Another recent publication reported that QCT could protect bone marrow-derived mesenchymal
stem cell from erastin-induced ferroptosis, possibly through the antioxidant pathway [19]. …

[HTML][HTML] Acute kidney injury

JA Kellum, P Romagnani, G Ashuntantang… - Nature reviews Disease …, 2021 - nature.com
… turn into tumour stem cells and set off monoclonal lesions in a papillary renal cell
adenoma−carcinoma sequence 81,83 . Kidney injuries to other nephron segments cause other types …

[PDF][PDF] Kidney damage in patients after allogeneic stem cell transplantation

M Kępska-Dzilińska, A Zhymaila, J Malyszko - Wiad Lek, 2022 - ppm.edu.pl
… The aim of the review is to present the most common renal complications after HSCT such
as acute kidney injury, chronic kidney disease glomerulopathies. HSCT is a critical therapy for …