Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality

D Legouis, SE Ricksten, A Faivre, T Verissimo… - Nature …, 2020 - nature.com
… Acute kidney injury stage 1 was defined as either a 1.5-fold increase in initial serum
creatinine level measured in the ICU, or a urine output <0.5 ml kg –1 h –1 over at least 6 …

Macrophages in renal injury, repair, fibrosis following acute kidney injury and targeted therapy

H Chen, N Liu, S Zhuang - Frontiers in immunology, 2022 - frontiersin.org
cells during the recovery phase after kidney injury (29). Another study shows that granulocyte
macrophage CSF (GM-CSF) mediates macrophage activation during the renal repair …

[PDF][PDF] Kidney damage in patients after allogeneic stem cell transplantation

M Kępska-Dzilińska, A Zhymaila, J Malyszko - Wiad Lek, 2022 - ppm.edu.pl
… The aim of the review is to present the most common renal complications after HSCT such
as acute kidney injury, chronic kidney disease glomerulopathies. HSCT is a critical therapy for …

Transfer of microRNA-216a-5p from exosomes secreted by human urine-derived stem cells reduces renal ischemia/reperfusion injury

Y Zhang, J Wang, B Yang, R Qiao, A Li… - Frontiers in cell and …, 2020 - frontiersin.org
… (E) Graph shows histologic kidney injury scores in the four groups of SD rats. *P < 0.05
versus sham, n = 4. (F) Graph depicts semiquantitative assessment of TUNEL staining in …

Wnt/β-catenin in acute kidney injury and progression to chronic kidney disease

T Huffstater, WD Merryman, LS Gewin - Seminars in nephrology, 2020 - Elsevier
kidney injury with the notable exception of T-cell differentiation, as will be discussed later.
A recent publication showed a protective effect of FoxO1 in the context of transforming growth …

POS-066 URINE-DRIVED STEM CELL ATTENUATE RENAL INFLAMMATION AND FIBROSIS AFTER RENAL ISCHEMIA REPERFUSION

JA Shin, JY Jeong, H Choi, DE Choi, EJ Lee… - Kidney International …, 2022 - kireports.org
… mice and DcR2 CKO mice were used to compare the degree of kidney injury, renal function
and tubular repair after I/R injury. Furthermore, quantitative proteomics and bioinformatics …

Models of sepsis-induced acute kidney injury

L Dong, YL Xie, RT Zhang, QY Hu - Life Sciences, 2024 - Elsevier
… UB organoids derived from either primary UB progenitor cells or human pluripotent stem
cells are amenable to effient gene editing, and have broad applications for studying …

Extracellular vesicles in kidney disease

C Grange, B Bussolati - Nature Reviews Nephrology, 2022 - nature.com
… as the beneficial effects of stem cell-derived extracellular vesicles in preclinical models of
acute kidney injury (AKI), chronic kidney disease (CKD) and kidney graft preconditioning. We …

Modeling injury and repair in kidney organoids reveals that homologous recombination governs tubular intrinsic repair

N Gupta, T Matsumoto, K Hiratsuka… - Science translational …, 2022 - science.org
… Human stem cell–derived kidney tissue represents an emerging technology that may … kidney
injury models and used human kidney biopsy samples from the most common kidney injury, …

Evaluation of cisplatin-induced injury in human kidney organoids

JLM Digby, T Vanichapol… - American Journal …, 2020 - journals.physiology.org
… Toward this goal, we have characterized induced pluripotent stem cell-derived human kidney
… In summary, our organoid model of cisplatin-induced kidney injury shows limited proximal …