TUNEL assay: a powerful tool for kidney injury evaluation
CL Moore, AV Savenka, AG Basnakian - International journal of molecular …, 2021 - mdpi.com
… of kidney cell injury. Nevertheless, TUNEL is becoming increasingly popular for kidney injury
… universally in cultured and tissue cells and for all mechanisms of cell death. Furthermore, it …
… universally in cultured and tissue cells and for all mechanisms of cell death. Furthermore, it …
Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis
J Wu, D Song, Z Li, B Guo, Y Xiao, W Liu, L Liang… - Cell research, 2020 - nature.com
… to treat lung injury and fibrosis. In this study, we report the generation of clinical-grade
human embryonic stem cells (hESCs)-derived immunity- and matrix-regulatory cells (IMRCs) …
human embryonic stem cells (hESCs)-derived immunity- and matrix-regulatory cells (IMRCs) …
The role of mitochondria in acute kidney injury and chronic kidney disease and its therapeutic potential
X Zhang, E Agborbesong, X Li - International journal of molecular …, 2021 - mdpi.com
… dysfunction contributes to the pathogenesis of different forms of kidney diseases, including
acute kidney injury (AKI) and chronic kidney disease (CKD). AKI has been linked to an …
acute kidney injury (AKI) and chronic kidney disease (CKD). AKI has been linked to an …
Mitochondria ROS and mitophagy in acute kidney injury
… Here, we summarized the role of activation of mitophagy during different causes of kidney
injury and the mechanism of mitophagy activation in the kidney, discuss the pharmacologic …
injury and the mechanism of mitophagy activation in the kidney, discuss the pharmacologic …
Renal Nano-drug delivery for acute kidney Injury: Current status and future perspectives
… agents (SMRA) to kidneys with acute injury were increasingly … kidney injury (AKI) from
prophylaxis-orientated to therapeutic orientated (outer ring) when they are delivered to the kidney …
prophylaxis-orientated to therapeutic orientated (outer ring) when they are delivered to the kidney …
Sepsis-associated acute kidney injury: consensus report of the 28th Acute Disease Quality Initiative workgroup
… Interventions related to cellular repair and fibrosis, including mesenchymal stem cell therapy
66 , protein-7 agonist 67 and mimetics of hepatocyte growth factor 68 , have been studied …
66 , protein-7 agonist 67 and mimetics of hepatocyte growth factor 68 , have been studied …
Cellular and molecular mechanisms of kidney injury in 2, 8-dihydroxyadenine nephropathy
BM Klinkhammer, S Djudjaj, U Kunter… - Journal of the …, 2020 - journals.lww.com
… kidneys, the tubular epithelial cells have a crystal-repulsive surface and urinary anions
coating the crystal surface prevent cellular … kidney injury is a switch of tubular epithelial cells …
coating the crystal surface prevent cellular … kidney injury is a switch of tubular epithelial cells …
[HTML][HTML] High–molecular weight hyaluronan attenuates tubulointerstitial scarring in kidney injury
… We propose that IL-10–induced HMW-HA synthesis plays cytoprotective and antifibrotic
roles in kidney injury, thereby revealing an effective strategy to attenuate renal fibrosis in …
roles in kidney injury, thereby revealing an effective strategy to attenuate renal fibrosis in …
Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair
KJ Mylonas, ED O'Sullivan, D Humphries… - Science translational …, 2021 - science.org
… kidney function and repair after injury. They found that ABT-263 targeted senescent proximal
tubular epithelial cells, and in aged mouse models of acute kidney injury, … tissue stem cells (…
tubular epithelial cells, and in aged mouse models of acute kidney injury, … tissue stem cells (…
Pum2-Mff axis fine-tunes mitochondrial quality control in acute ischemic kidney injury
… kidney injury. Our results indicated that genetic deletion of Mff overtly attenuated ischemic
acute kidney injury (… oxidative stress, and ultimately cell death in the kidney. Furthermore, Mff …
acute kidney injury (… oxidative stress, and ultimately cell death in the kidney. Furthermore, Mff …