… Here, we investigate the detailed structure–activity relationships of the ligand-bound
receptor complexes that underlie both potent activation by the natural ligand and cross-reactivity. …

… receptors, tachykinins … on structure–activity relationships established the importance of the
specific chemical characteristics of neurokinins that are necessary to trigger their receptors [4]. …

… , accounting for ~30% of the receptors in class A and 100% of the receptors in class B1 [4].
Examples include the endorphins, tachykinins, members of the secretin family, ghrelin, …

… , the author describes structure-activity relationship studies of … 2, the author describes a
structure-activity relationship study … to investigate the structure-activity relationships of fezolinetant …

… The tachykinin (TK) peptide family is one of the most … selective binding and activation of
tachykinin receptors (wherein X is an … An additional structure-activity relationship study of this hit …

… the structure and function of NKB receptors. Based on an in silico model of the tilapia NKB
receptor Tachykinin 3 receptor a (… to tiNKB/tiNKF-induced receptor activity. The binding of NKB …

Locoregionally administered, NK1 receptor (NK1R) targeted radionuclide therapy is a promising
strategy for the treatment of glioblastoma multiforme. So far, the radiopharmaceuticals …

… feature of tachykinins occurring in all vertebrates and invertebrates (2), and its removal has
been demonstrated to be detrimental to agonist activity of SP (47, 48). In the structures of SP-…

… Modification of the tachykinin peptides can significantly alter their receptor … Structure–activity
relationship studies have revealed that the common C-terminal motif of the tachykinins (Phe–…

… investigate relationships of the Hdh-TKRs with other bilaterian TKRs and related receptors,
… the NCBI database with bilaterian TKRs and sNPF receptors as an outgroup. This analysis …