Drug delivery to macrophages: a review of targeting drugs and drug carriers to macrophages for inflammatory diseases
… inflammatory diseases, summarize the leading drugs used to regulate macrophages, and
review drug delivery systems designed to target … macrophage-targeted drug delivery systems. …
review drug delivery systems designed to target … macrophage-targeted drug delivery systems. …
The cGAS–STING pathway as a therapeutic target in inflammatory diseases
A Decout, JD Katz, S Venkatraman… - Nature Reviews …, 2021 - nature.com
… , we examine pharmacological intervention strategies that target this pathway and discuss
their therapeutic potential in the treatment of inflammatory and autoinflammatory diseases. …
their therapeutic potential in the treatment of inflammatory and autoinflammatory diseases. …
Mechanisms and therapeutic regulation of pyroptosis in inflammatory diseases and cancer
Z Zheng, G Li - International journal of molecular sciences, 2020 - mdpi.com
… of pyroptosis as a therapeutic target in human diseases. Blockade of pyroptosis by compounds
can treat inflammatory disease and pyroptosis activation contributes to cancer therapy. …
can treat inflammatory disease and pyroptosis activation contributes to cancer therapy. …
[HTML][HTML] NLRP3 inflammasome and inflammatory diseases
Z Wang, S Zhang, Y Xiao, W Zhang, S Wu… - … medicine and cellular …, 2020 - hindawi.com
… plays a vital role in regulating inflammation. In this review, NLRP3 … in inflammatory diseases,
interactions with autophagy, and targeted therapeutic approaches in inflammatory diseases …
interactions with autophagy, and targeted therapeutic approaches in inflammatory diseases …
[HTML][HTML] A pH/ROS dual-responsive and targeting nanotherapy for vascular inflammatory diseases
R Zhang, R Liu, C Liu, L Pan, Y Qi, J Cheng, J Guo… - Biomaterials, 2020 - Elsevier
… (B) Engineering of a dual-responsive, targeting rapamycin nanotherapy based on a pH-…
material (OCD) as well as targeted treatment of a vascular inflammatory disease of restenosis. …
material (OCD) as well as targeted treatment of a vascular inflammatory disease of restenosis. …
Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles
RQ Yao, C Ren, ZF Xia, YM Yao - Autophagy, 2021 - Taylor & Francis
… range of diseases, varying from inflammatory disease to … as well as the development of
various diseases ( Table 2 ). It is … will be a potential therapeutic target for maintaining cell viability …
various diseases ( Table 2 ). It is … will be a potential therapeutic target for maintaining cell viability …
Targeting cancer-promoting inflammation—have anti-inflammatory therapies come of age?
… Thus, the use of anti-inflammatory agents, either alone or in combination with cytotoxic
agents and targeted therapies, is an appealing strategy for the treatment of inflammation-driven …
agents and targeted therapies, is an appealing strategy for the treatment of inflammation-driven …
Inflammasomes as therapeutic targets in human diseases
Y Li, H Huang, B Liu, Y Zhang, X Pan, XY Yu… - … and targeted therapy, 2021 - nature.com
… In this review, we summarized the link between inflammasomes and sterile inflammatory
diseases, including CVDs, depression, neurodegenerative diseases, diabetes, and cancer. …
diseases, including CVDs, depression, neurodegenerative diseases, diabetes, and cancer. …
Janus kinase-targeting therapies in rheumatology: a mechanisms-based approach
… diseases (Table 1). In this Review we describe the progress in JAK-targeting therapies for
autoimmune rheumatic diseases, … of action, and discussion on a disease-by-disease basis. …
autoimmune rheumatic diseases, … of action, and discussion on a disease-by-disease basis. …
[HTML][HTML] … on viral replication and virus infection-induced inflammatory responses: a promising therapeutic target for virus infection-induced inflammatory diseases
X Ding, S Li, L Zhu - Cytokine & growth factor reviews, 2021 - Elsevier
… Application of HMGB1 inhibitors or neutralization antibody alleviates disease progression
in vivo HMGB1 is recognized as a therapeutic target for the treatment of inflammatory diseases …
in vivo HMGB1 is recognized as a therapeutic target for the treatment of inflammatory diseases …
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