Emerging pharmacotherapy for inflammatory bowel diseases
H Luo, G Cao, C Luo, D Tan, CT Vong, Y Xu… - Pharmacological …, 2022 - Elsevier
… We have summarized the emerging therapeutic methods for IBD, including new targeted
biological and small molecule drugs, microbiota-targeting therapies, and traditional Chinese …
biological and small molecule drugs, microbiota-targeting therapies, and traditional Chinese …
The microbiome in inflammatory bowel diseases: from pathogenesis to therapy
… therapeutic approaches targeting microbiome, which is a promising strategy to alleviate and
cure this inflammatory disease… of IBD and the potential therapeutic options that target the gut …
cure this inflammatory disease… of IBD and the potential therapeutic options that target the gut …
Selective targeting of TNF receptors as a novel therapeutic approach
R Fischer, RE Kontermann… - Frontiers in cell and …, 2020 - frontiersin.org
… However, the involvement of LTα in inflammatory diseases is less well characterized than
sTNF … as a therapeutic target for arthritis and potentially other inflammatory diseases as well. …
sTNF … as a therapeutic target for arthritis and potentially other inflammatory diseases as well. …
Targeting immunometabolism as an anti-inflammatory strategy
EM Pålsson-McDermott, LAJ O'Neill - Cell research, 2020 - nature.com
… in activated immune cells such as M1 macrophages, B cells, NK cells, DCs and Th17 cells,
99,100 making it an attractive therapeutic target in cancer as well as inflammatory disease. …
99,100 making it an attractive therapeutic target in cancer as well as inflammatory disease. …
Targeting JAK/STAT signaling pathways in treatment of inflammatory bowel disease
L Wang, Y Hu, B Song, Y Xiong, J Wang, D Chen - Inflammation Research, 2021 - Springer
… sufficient capacity to target various signaling pathway molecules and have great potential
for disease treatment. In this paper, we summarize the natural products that can target the JAK/…
for disease treatment. In this paper, we summarize the natural products that can target the JAK/…
NLRP3 and pyroptosis blockers for treating inflammatory diseases
… inflammation in many diseases and is an exciting drug target. Here, we review the
molecular basis of NLRP3 inhibition by drug-like small molecules under development as novel …
molecular basis of NLRP3 inhibition by drug-like small molecules under development as novel …
[HTML][HTML] Ferroptosis as an emerging target in inflammatory diseases
H Mao, Y Zhao, H Li, L Lei - Progress in biophysics and molecular biology, 2020 - Elsevier
… for ferroptosis and inflammatory diseases, underlying … light on the etiology and treatment
of inflammatory diseases. … role in inflammatory diseases will be discussed in this review. …
of inflammatory diseases. … role in inflammatory diseases will be discussed in this review. …
Immunological mechanisms and therapeutic targets of fatty liver diseases
… latest concepts regarding the roles of various inflammatory cells in the occurrence and
development of NAFLD and discuss potential immune cell-targeted therapies for NAFLD (Fig. 2). …
development of NAFLD and discuss potential immune cell-targeted therapies for NAFLD (Fig. 2). …
Programming inflammatory cell death for therapy
S Christgen, RE Tweedell, TD Kanneganti - Pharmacology & therapeutics, 2022 - Elsevier
… cell death in health and disease, with a particular focus on … of inflammatory cell death.
Further, we discuss the implications and feasibility of targeting these molecules to improve disease …
Further, we discuss the implications and feasibility of targeting these molecules to improve disease …
The NLRP3 inflammasome pathway: a review of mechanisms and inhibitors for the treatment of inflammatory diseases
… in several inflammatory diseases. Studies using small molecules and biologics targeting the
… outcomes in treating various disease pathologies by blocking chronic inflammation. In this …
… outcomes in treating various disease pathologies by blocking chronic inflammation. In this …