… , inflammatory diseases, and an increased burden of aging cells with advancing age. While
age does not seem to affect the number of NK progenitors in the peripheral blood or bone …

… inflammatory mediators have hampered therapeutic implementation of therapeutic strategies
targeting the inflammatory … of the complex role of inflammation in heart disease, and the …

… and drugs that target Janus kinases (JAKs) presumably involved in the pathogenesis of
immune-mediated inflammatory diseases (IMIDs). Top: efficacy of agents targeting specific JAK-…

… target tissues to inflammatory mediators; reversing the effect of the medium on the target tissue;
produce anti-inflammatory … , the inflammatory mechanism of above diseases, therapeutic …

… This review illustrates the clinical relevance of IL-1α to the pathogenesis of inflammatory
diseases, as well as the rationale for the targeted inhibition of this cytokine for treatment of these …

… inflammatory diseases in various organs and potential therapeutic/preventive strategies that
target … We also discuss ILCs’ involvement in human inflammatory diseases in various organs …

… sterile inflammation. HMGB1-targeted therapies in several sterile inflammatory diseases
including I/R injury, ischemia, pancreatitis, and autoimmune disease, have been extensively …

… targeting of immune pathways in IMIDs, it was recognized that the best disease outcomes
occur when inflammation is … aggressive use of targeted therapies to control inflammation 5,20 . …

… It can be said that therapeutic interventions targeting leptin might potentially prevent or …
a role for apelin system in cardiovascular diseases, making it an attractive therapeutic target. …

… of diseases that goes beyond its approved indications for rheumatoid arthritis and
cryopyrin-associated periodic syndromes, to encompass cancer and chronic inflammatory diseases …