… an overview of sepsis immune pathophysiology, to update the choice of therapeutic approaches
targeting different immunological mechanisms in the course of sepsis and septic shock, …

… The therapies and procedures for attenuating sepsis-induced brain … of sepsis-induced brain
damage, its diagnosis, the role of critical inducers and mediators and, ultimately, therapeutic …

… therapies). Here, because the potential use of anti-inflammatory therapies in the treatment
of COVID-19 patients, we revisited the previous use of these therapies in sepsis settings. …

… To cast light on sepsis pathogenesis and novel intervention therapeutic results, we systemically
… and focused on the molecular signaling pathways and intervention therapies in sepsis. …

… The highest reduction in mortality was observed in patients with septic shock who received
appropriate antimicrobial therapy within 1 hour from sepsis recognition (35). A randomized …

… Management of the patient with sepsis comprises three key … all patients with sepsis and will
include antibiotic therapy and … of the host response to sepsis have yet been shown to improve …

… is a significant event in sepsis and septic shock leads to the … could be a promising therapeutic
approach. Within the intricate web of … The clinical rationale for IVIg therapy in sepsis can be …

… the molecular mechanisms of a human disease or at proposing new therapeutic approaches
to improve health outcome. Laboratory animals are often used to mimic human diseases. …

… and damage to the lung endothelial barrier during sepsis. Thus, inhibition of caspases-4/5/1 …
therapeutic approach in adjunction with neutralizing extracellular LPS for treatment of sepsis…

… are in an urgent need for a multi-targeting therapeutic approach for sepsis. … sepsis
pathogenesis, lessons learned, and the future therapeutic/early diagnostic approaches to target …