… Furthermore, as ICB and CAR-T cells have been the most rigorously evaluated immunotherapy
strategies in the clinic, we will also discuss biomarkers associated with the clinical …

… , no biomarkers for stroke are available to use in clinical … , identification of therapeutic targets
and biomarker discovery. … stroke and the current status of biomarker research in stroke. We …

… their target genes [282]. … biomarkers for diagnosis or therapeutic targets in endothelial
dysfunction [283]. Difficulties concerning the clinical use of miRNAs derive from their multiple target …

… as prognostic biomarkers. We also describe potential therapeutic strategies to target Tregs
in … to overcome tumor resistance and improve clinical outcomes in cancer patients. Overall, …

… biomarkers for early diagnosis, prognosis and assessment of liver diseases and discuss the
challenges in miRNA-based therapy … and may identify biomarkers and therapeutic targets for …

… with potential circulating biomarkers and therapeutic targets for a host of human diseases. …
up their investigation in liquid biopsies as sources of biomarkers and therapeutic targets. …

… , is the primary therapeutic target for … therapeutic target in clinical practice. Ongoing coronary
artery disease residual risk, despite lipid-lowering treatment, has left patients and clinicians …

… in ECM remodeling and represent an interesting target for therapeutic drug discovery. In this
… their role as biomarkers. Finally, we highlight MMPs as promising therapeutic targets for the …

… The pleiotropic roles of CD44 in carcinoma potentially offering new molecular target for
therapeutic intervention. Preclinical and clinical trials for evaluating the pharmacokinetics, …

… clinical application of sorafenib is limited by tumor heterogeneity, tumor escape, and the lack
of predictive biomarkers … dose-reduction of sorafenib, clinical monitoring is necessary for the …