Contemporary antiretrovirals and body-mass index: a prospective study of the RESPOND cohort consortium

L Bansi-Matharu, A Phillips, C Oprea… - The Lancet …, 2021 - thelancet.com
… received at or after RESPOND entry, changes from pre-antiretroviral BMI levels (baseline)
were considered at each BMI measurement during antiretroviral treatment. We used logistic …

Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response

SHR Lee, W Yang, Y Gocho, A John, L Rowland… - Nature medicine, 2023 - nature.com
treatment response as measured by MRD in the context of contemporary ALL treatment
regimens… populations based on genetic ancestry composition and defined as: European (…

A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia

AGX Zeng, S Bansal, L Jin, A Mitchell, WC Chen… - Nature medicine, 2022 - nature.com
patients. Without measuring these cellular hierarchies at scale in large clinical datasets, the
relationship of hierarchy composition to therapy response … of combination regimens through …

Optimal control theory for personalized therapeutic regimens in oncology: Background, history, challenges, and opportunities

AM Jarrett, D Faghihi, DA Hormuth, EABF Lima… - Journal of clinical …, 2020 - mdpi.com
… chemical composition, resulting in permanent damage. In poorly oxygenated tissue, there
is insufficient oxygen to react with the produced free radicals, and the chemical composition of …

Multicenter comparison of molecular tumor boards in the Netherlands: definition, composition, methods, and targeted therapy recommendations

B Koopman, HJM Groen, MJL Ligtenberg… - The …, 2021 - academic.oup.com
… in the routine diagnostic … treating physicians in understanding the increasing complexity
of molecular testing results, providing rational, genomics-driven, patient-tailored treatment

[HTML][HTML] Redefining breast cancer subtypes to guide treatment prioritization and maximize response: Predictive biomarkers across 10 cancer therapies

DM Wolf, C Yau, J Wulfkuhle, L Brown-Swigart… - Cancer Cell, 2022 - cell.com
… ) status to better predict drug responses. We assess the predictive … patients treated with 10
regimens targeting diverse biology. We explore >11 subtyping schemas and identify treatment

Standardised shorter regimens versus individualised longer regimens for rifampin-or multidrug-resistant tuberculosis

S Abidi, J Achar, MMA Neino, D Bang… - European …, 2020 - Eur Respiratory Soc
… to those using either moxifloxacin or levofloxacin (as gatifloxacin is no longer available)
and we restricted longer regimens to those whose composition met 2018 WHO guidelines by …

Relative Dose Intensity of Chemotherapy and Survival in Patients with Advanced Stage Solid Tumor Cancer: A Systematic Review and Meta-Analysis

CM Nielson, LC Bylsma, JP Fryzek, HA Saad… - The …, 2021 - academic.oup.com
… to optimal treatments and dosing regimens for patients with cancer [1, 2]. Although most
chemotherapy regimens are dosed based on patient-… Body composition was found to be a major …

[HTML][HTML] Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose?

S Demaria, C Guha, J Schoenfeld, Z Morris… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
… and unique multifractionated radiotherapy regimens, as these … testing different radiation
therapy regimens as separate models … of frequently used 8 Gy×3 regimens immunomodulation. …

Patient-derived organoids as a predictive biomarker for treatment response in cancer patients

GE Wensink, SG Elias, J Mullenders… - NPJ precision …, 2021 - nature.com
… review used varying medium compositions. Depending on … tumour type medium compositions
and culturing techniques … resemble combination treatment regimens given to patients 45 . …