Pretomanid in drug-resistant tuberculosis: a profile of its use

M Shirley - Drugs & Therapy Perspectives, 2020 - Springer
… of the regimen composition may be necessary or appropriate. Besides drug susceptibility, …
in making treatment regimen decisions, including drug-specific mycobactericidal activity, …

[HTML][HTML] Novel approaches for the treatment of pulmonary tuberculosis

ZM Tan, GP Lai, M Pandey, T Srichana, MR Pichika… - Pharmaceutics, 2020 - mdpi.com
… The standard TB treatment is to strictly follow six months of drug regimen provided with patient
support … PZA was incorporated with different other anti-tuberculosis drugs to treat TB. The …

[HTML][HTML] The war against tuberculosis: A review of natural compounds and their derivatives

M Maiolini, S Gause, J Taylor, T Steakin, G Shipp… - Molecules, 2020 - mdpi.com
… As noted, multiple drugs are required to treat TB disease and these extended drug regimens
are challenging to both patients and health care systems [1]. Extensively drug-resistant (…

[HTML][HTML] Comparison of different regimens with or without fluoroquinolone in isoniazid-resistant tuberculosis: A multicenter cohort study

J Min, HW Kim, JY Kang, SK Kim, JW Kim, YH Kim… - Plos one, 2022 - journals.plos.org
… High-quality studies are necessary to optimize the composition and duration of Hr-TB
regimens, particularly of Fqs and reducing the duration of pyrazinamide. Anti-TB treatment …

Examining nonadherence in the treatment of tuberculosis: The patterns that lead to failure

WS Fox, N Strydom, MZ Imperial… - British Journal of …, 2023 - Wiley Online Library
… Missing doses during treatment can lead to disease relapse and tuberculosis drug … Baseline
characteristics, regimen composition, adherence and clinical outcome data as defined by …

[HTML][HTML] Evolution of Drug-Resistant Mycobacterium tuberculosis Strains and Their Adaptation to the Human Lung Environment

A Allué-Guardia, JI García, JB Torrelles - Frontiers in Microbiology, 2021 - frontiersin.org
… Only a few studies have explored the cell envelope composition of drug-resistant M.tb
strains and their metabolic responses and adaptation to the different environmental pressures …

Nano-based drug delivery optimization for tuberculosis treatment: A review

MH Dahanayake, ACA Jayasundera - Journal of Microbiological Methods, 2021 - Elsevier
… of drug regimen could be achieved with improved drug encapsulation capacity, better drug
loading, improved bioavailability, duration of retention in organs, and releasing the drugs in a …

[HTML][HTML] Gut microbiota composition and diversity before, during, and two months after rifamycin-based tuberculosis preventive therapy

MN Séraphin, J Bellot, E Klann, M Ukhanova… - Scientific Reports, 2023 - nature.com
… Shorter TPT regimens can increase treatment compliance as … regimens are currently approved
for use, including regimens … A one-month regimen of INH and RPT has been shown to be …

… of Drug Induced Hepatotoxicity Incident of Fixed-Dose Combination and Separate Formulations Regimen for Pulmonary Tuberculosis Treatment in Hospital …

S Nurafni, N Sari, F Mulyani - Journal of Physics: Conference …, 2021 - iopscience.iop.org
… aid and prevents the development of drug resistence, has been approved as a standarad
anti-TB treatment regimen. However, the composition and contribution of doses for FDC …

[HTML][HTML] Sequencing Mycobacteria and Algorithm-determined Resistant Tuberculosis Treatment (SMARTT): a study protocol for a phase IV pragmatic randomized …

A Van Rie, E De Vos, E Costa, L Verboven, F Ndebele… - Trials, 2022 - Springer
… -line drugs, the challenges in translating WGS results into individualized treatment regimen
composition… resistance genes for 13 anti-tuberculosis drugs: the four first-line drugs (RIF, INH, …