… growth factor (HGF), fibroblast growth factor (FGF), vascular endothelial growth factor (VEGF),
and insulin-like growth factor … and invasion thereby promoting tumor growth, angiogenesis, …

… of oxygen, nutrients, and growth factors as well as tumor dissemination to distant organs. …
solid tumors that depend on cutting or at least reducing the blood supply to tumor micro-…

… therapies [5]. Anti-angiogenic therapies targeting the vascular endothelial growth factor (…
angiogenesis therapy [7] and tumor prevention based on its expression in blood vessels [8]. …

… Vascular endothelial growth factor (VEGF) is a key mediator of tumor angiogenesis … factor
and its receptor [29]. TAMs induce various growth factors such as basic fibroblast growth factor, …

… Higher self-renewal ability (stemness) of CSCs, which means more CSCs in the tumor,
indicates a higher possibility of anti-tumor therapy resistance. CAF-secreted TGF-β2 activated …

… be associated with increased levels of vascular endothelial growth factor and that inhibiting
angiogenesis could contribute to tumor growth inhibition. Under the selective pressure of …

… maintain the tumor growth. A … tumor tissue, which releases abundant growth factors and
cytokines, stimulating angiogenesis and lymphangiogenesis to meet the needs of tumor growth …

… the majority of tumor cells in human malignant tumors [9, 22] and this will be the highlighted
topic of the current review. As mentioned, MDK functions as a cytokine and growth factor with …

… and tumor suppressors that primarily affect a handful of signal transduction pathways, most
importantly the growth factor … targeted therapeutics against growth factor signaling have had …

… CAR T cells in solid tumors. Given that Flt3L is a critical growth factor for DCs 6 , we hypothesized
that armored T cells engineered to secrete Flt3L can overcome tumor heterogeneity by …