Islet expression of type I interferon response sensors is associated with immune infiltration and viral infection in type 1 diabetes
PS Apaolaza, D Balcacean, J Zapardiel-Gonzalo… - Science …, 2021 - science.org
… for six pathways: Staphylococcus aureus infection, type 1 diabetes mellitus, allograft
rejection, … aureus infection, which encodes various proteins involved in immune response and …
rejection, … aureus infection, which encodes various proteins involved in immune response and …
Type I natural killer T cells as key regulators of the immune response to infectious diseases
… an optimal response upon detection of antigens. The cells comprising the immune response
are … into two major subsets, innate and adaptive, with particular characteristics for each type. …
are … into two major subsets, innate and adaptive, with particular characteristics for each type. …
Early events triggering the initiation of a type 2 immune response
DW El-Naccache, G Haskó, WC Gause - Trends in immunology, 2021 - cell.com
… PAMPs binding TLRs can initiate type 1 and type 17 innate immune responses through the
… in initiating the type 2 immune response. Instead, the innate type 2 response appears more …
… in initiating the type 2 immune response. Instead, the innate type 2 response appears more …
Type 1 diabetes mellitus as a disease of the β-cell (do not blame the immune system?)
BO Roep, S Thomaidou, R van Tienhoven… - Nature Reviews …, 2021 - nature.com
… Consistently, patients with cancer who are treated with immune checkpoint inhibitors (that
is… immune regulation and initiating an immune response against the tumour tissue (Fig. 1) are …
is… immune regulation and initiating an immune response against the tumour tissue (Fig. 1) are …
Identification of immune activation markers in the early onset of COVID-19 infection
JJ Kovarik, AK Kämpf, F Gasser, AN Herdina… - … cellular and infection …, 2021 - frontiersin.org
… respiratory infections with … immune response of the host, early after COVID-19 infection and
ultimately might help to develop innovative therapeutic strategies against COVID-19 infection…
ultimately might help to develop innovative therapeutic strategies against COVID-19 infection…
[HTML][HTML] Type-1 immunity and endogenous immune regulators predominate in the airway transcriptome during chronic lung allograft dysfunction
… Our findings demonstrate a significant and differential Type-1 immune activation signature
in the airway transcriptome and BAL proteome from CLAD LTRs, compared to stable LTR …
in the airway transcriptome and BAL proteome from CLAD LTRs, compared to stable LTR …
Type I interferon (IFN)-regulated activation of canonical and non-canonical signaling pathways
C Mazewski, RE Perez, EN Fish… - Frontiers in …, 2020 - frontiersin.org
… and the dysregulated immune response. Figure 2 summarizes the cell type-specific type I
IFN-… Progression of type 1 diabetes from the prediabetic stage is controlled by interferon-alpha …
IFN-… Progression of type 1 diabetes from the prediabetic stage is controlled by interferon-alpha …
IRF1 promotes the innate immune response to viral infection by enhancing the activation of IRF3
J Wang, H Li, B Xue, R Deng, X Huang, Y Xu… - Journal of …, 2020 - Am Soc Microbiol
… a role in innate immunity is unclear. In this study, we demonstrated that IRF1 promotes the
innate immune response to viral infection. IRF1 is induced by viral infection. Notably, IRF1 …
innate immune response to viral infection. IRF1 is induced by viral infection. Notably, IRF1 …
Constitutive immune mechanisms: mediators of host defence and immune regulation
… during the initial stages of an infection, which prevents the … otherwise activate an inducible
immune response through … disease caused by infections with herpes simplex virus type 1, …
immune response through … disease caused by infections with herpes simplex virus type 1, …
Cytomegalovirus latency and reactivation: an intricate interplay with the host immune response
… , and injury that are common to many cell types, … immune response, in which it exploits cell
type specific mechanisms of gene regulation to establish latency and to disseminate infection …
type specific mechanisms of gene regulation to establish latency and to disseminate infection …
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