… In this review, we reviewed the underlying mechanisms of PARP inhibitor resistance in
detail and summarized the potential strategies to overcome PARPi resistance and increase …

Pain can be both a cause and a consequence of sleep deficiency. This bidirectional relationship
between sleep and pain has important implications for clinical management of patients, …

… Therefore, we recommend considering the fluctuations in TSH levels and their potential
underlying biological mechanisms in clinical practice and when performing clinical research. For …

… This review will discuss current contemporary knowledge of the causes and underlying
mechanisms in adiposity and associated cardiovascular disease (CVD), with an ultimate aim to …

… developing takotsubo syndrome, 15 the underlying mechanism remains unknown, but can
… syndrome are women, 15,20 the mechanism underlying this large sex disparity is unknown. …

… Troponin and brain natriuretic peptides, together with the presence of underlying
cardiovascular diseases or cardiovascular risk factors, are highly prognostic of the requirement for …

… As discussed in this review, multiple underlying mechanisms and numerous molecular targets
are involved in DIC, and each of them is concluded to be a significant cause of DIC by the …

… underlying mechanism of tumor growth inhibition. Subsequent studies, however, demonstrated
that this hypothesis fails to capture the complex and varied effects of VEGF-A inhibition, …

… The authors conclude that a better understanding of the factors and mechanisms
underlying the connection of periodontitis and osteoporosis may lead to an interdisciplinary …

Common manifestations of COVID-19 are respiratory and can extend from mild symptoms to
severe acute respiratory distress. The severity of the illness can also extend from mild …