… , as well as respiratory drive, increases during apnea and … and instability of the respiratory
center control, whereas those … and relatively stable respiratory control. The overshoot and …

… Background In the classic model of obstructive sleep apnoea (OSA), respiratory events
occur with sleep-related dilator muscle hypotonia, precipitating increased neural ventilatory ‘drive’…

… The pattern of recurring apnea frequently observed in OSA supports an instability of
ventilatory control similar to periodic breathing and upper airway obstruction is most likely when …

… always occur during sleep [10]. … with sleep-related reductions in respiratory control and
chemoresponsiveness are probably important contributors. People with obstructive sleep apnoea …

… collapsibility in REM sleep (lower ventilation at eupneic drive [ie… the ventilation–drive
relationship characterizing sleep apnea … to rising ventilatory drive stimuli is presumed in REM …

… obstructive sleep apnea (OSA). It is estimated that moderate–severe sleep-disordered
breathing (SDB; ie, apnea–… -19–related sepsis or acute respiratory distress syndrome (ARDS). …

… Obstructive sleep apnea (OSA) is a common chronic condition affecting more than 1 billion …
apnea–hypopnea index (AHI), which is the frequency of respiratory events defined by apneas …

… Loop Gain (LG): Measures instability in ventilatory control, by measuring the ratio of
ventilatory response to a steady-state ventilatory disturbance. The disturbance is the increase in …

… Aside from many other factors, OSA is influenced by an instability of the ventilatory drive, which
… ventilatory control system, resulting in overshooting and undershooting of the ventilation. …

… HSAT is typically accomplished using a Level III modified portable sleep apnea test which
measures air flow, respiratory effort, oxygen saturation, and heart rate; it does not include EEG …