… Ceramide can be key for the formation of viral replication sites. Sphingomyelinases often …
ceramide synthesis enhances IAV replication [121], and exogenous ceramide reduces viral …

… ceramide transfer protein (CERT), which is in the SM biosynthesis pathway, are essential for
the biosynthesis of double-membrane vesicles (DMVs), the sites of viral … ceramide synthesis …

… to decreased influenza virus infection [23–25,34]. Conversely, reductions in ceramide
synthesis through inhibition of ceramide synthase led to an increase in influenza virus replication […

… ceramide synthase (CerS) enzymes that produce ceramides, … In many cell types, CerS2,
which catalyzes the synthesis of … into virus particles, but it reduced the infectivites of viruses …

… ceramide levels are related to liver cirrhosis and viral genotype. Whether the more favorable
serum ceramide … Mice deficient in ceramide synthase 2 are unable to synthesize very-long-…

… ATL is an aggressive neoplasm that develops following infection with human T-cell
lymphotropic virus-1 (HTLV-1) where the viral oncogene Tax contributes to the pathogenesis of the …

… the newly synthesized viral particles … virus via ceramide flux—a key mediator of Zika infection
[59]. A recent study demonstrated that Zika virus requires host glycosphingolipids for viral …

… that Epstein-Barr virus infection leads to a reduction in ceramide levels. Additionally… ceramide
levels. This study reports the regulation of lytic replication by ceramide in Epstein-Barr virus…

… with a specific inhibitor of ceramide synthesis impaired TBEV replication. These findings
suggested that suppression of the de novo sphingolipid synthesis pathway could be a …

… for ceramide synthesis, ceramide accumulation in the ER leads to cell death. Thus, ceramide
… by flavivirus, either West Nile virus or Dengue virus, had elevated ceramide levels [86,87] …