… In this study, we examined whether the synthesis of glycosphingolipids, major membrane …
neuroinvasive Sindbis virus replication, as treating infected cells with UDP-glucose ceramide …

… COVID-19, ceramide plays a central role during viral cell entry. … of ceramide biosynthesis,
suppress viral replication [9]. … synthesis and esterification, LD formation, and ceramide …

… Within membranes, ceramides serve to enhance both lateral membrane organization and …
Ceramide synthesis can take place via several different pathways: de novo synthesis in the ER…

… In infected cells, SPHK1 was shown to promote viral RNA synthesis by activating NF-κB
and to maintain CRM1/RanBP3-mediated nuclear export of the viral ribonucleoprotein (vRNP) …

… We intraperitoneally injected myriocin to inhibit de novo ceramide synthesis in the HF-fed
mice. The liver weight/body weight rate showed no significant reduction (Fig. 5C). …

… enzyme of Cer synthesis, Cer synthase (CERS) is the primary enzyme of ceramide synthesis.
The … for attachment of many infectious viruses [98, 99]. On the other hand, Neuα5Gc is not …

… synthesis (FAS) are increased during VACV infection of BMDMs, in contrast to what was
observed for cell types … might be different between cell types. Interestingly, proteins involved in …

… and as well as virus associated factors such as viral load … Ceramide profile in lipid extracts
obtained from RBC and from serum samples. In patients with COVID-19, ceramide synthesis …

… ceramide synthesis (known as the sphingolipid salvage pathway) (reviewed in reference 35).
Even if sphingosine and ceramide … to be involved in the bulk synthesis of SM in cells (4, 13)…

… drugs, cytotoxic drugs, hypoxia microenvironment, malnutrition, radiotherapy and hyperthermia
can promote the apoptosis of tumor cells by promoting the activity of ceramide synthesis …