Clinical and economic burden of chronic heart failure and reduced ejection fraction following a worsening heart failure event

J Butler, LM Djatche, B Sawhney, S Chakladar… - Advances in …, 2020 - Springer
… event (WHFE) is defined as progressively escalating heart failure signs/symptoms … chronic
heart failure with reduced ejection fraction (HFrEF) following a WHFE versus stable disease

Effect of empagliflozin on worsening heart failure events in patients with heart failure and preserved ejection fraction: EMPEROR-preserved trial

M Packer, J Butler, F Zannad, G Filippatos, JP Ferreira… - Circulation, 2021 - Am Heart Assoc
heart failure events. We and others have reported that in patients with heart failure with reduced
ejection fraction, … the risk of hospitalization for heart failure, but also diminished the risk of …

Worsening heart failure episodes outside a hospital setting in heart failure with preserved ejection fraction: the PARAGON-HF trial

M Vaduganathan, JW Cunningham, BL Claggett… - Heart Failure, 2021 - jacc.org
… This study sought to evaluate the frequency and prognostic implications of urgent heart
failure (HF) visits in a large global clinical trial of HF with preserved ejection fraction (HFpEF). …

Effect of dapagliflozin on outpatient worsening of patients with heart failure and reduced ejection fraction: a prespecified analysis of DAPA-HF

KF Docherty, PS Jhund, I Anand, O Bengtsson… - Circulation, 2020 - Am Heart Assoc
… in patients with heart failure and reduced ejection fraction (HFrEF) is the composite of time to
hospitalization for worsening heart failure or cardiovascular … treating worsening heart failure

Resource utilization and costs among patients with heart failure with reduced ejection fraction following a worsening heart failure event

MM Givertz, M Yang, GP Hess, B Zhao, A Rai… - … Heart Failure, 2021 - Wiley Online Library
… In the present study, 20% of patients who experienced a worsening heart failure event had
heart failure-related hospital readmissions within 30 days after the worsening event, and 32% …

Effect of empagliflozin on the clinical stability of patients with heart failure and a reduced ejection fraction: the EMPEROR-Reduced trial

M Packer, SD Anker, J Butler, G Filippatos, JP Ferreira… - Circulation, 2021 - Am Heart Assoc
… In conclusion, in patients with heart failure and a reduced ejection fraction, empagliflozin
reduced the risk of inpatient and outpatient worsening heart failure events, benefits that were …

Renal function and the effects of vericiguat in patients with worsening heart failure with reduced ejection fraction: insights from the VICTORIA (Vericiguat Global Study …

AA Voors, H Mulder, E Reyes… - … of Heart Failure, 2021 - Wiley Online Library
… dysfunction, worsening renal function, and hyperkalaemia are frequently present in patients
with heart failure (HF) with reduced ejection fraction (HFrEF), especially those with severe HF…

[HTML][HTML] Patients hospitalized for de novo versus worsening chronic heart failure in the United States

SJ Greene, TS Triana, R Ionescu-Ittu, S Shi… - Journal of the American …, 2021 - jacc.org
… Patients hospitalized for heart failure with reduced ejection fraction (HFrEF) can be divided
into those with de novo heart failure (HF) versus those with worsening chronic heart failure (…

Angiotensin-neprilysin inhibition in patients with mildly reduced or preserved ejection fraction and worsening heart failure

RJ Mentz, JH Ward, AF Hernandez, S Lepage… - Journal of the American …, 2023 - jacc.org
… ) in patients with heart failure (HF) and ejection fraction (EF) … EF or patients with heart failure
with preserved ejection (… how best to utilize Sac/Val in patients with HF and EF >40% has …

Cost effectiveness of vericiguat for the treatment of chronic heart failure with reduced ejection fraction following a worsening heart failure event from a US Medicare …

A Alsumali, LM Djatche, A Briggs, R Liu, I Diakite… - …, 2021 - Springer
… Given the high economic burden of disease among adult patients with chronic heart failure
with reduced ejection fraction (HFrEF) following a worsening heart failure event in the US, …