Novel isoquinolone PDK1 inhibitors discovered through fragment-based lead discovery

MC Johnson, Q Hu, L Lingardo, RA Ferre… - Journal of computer …, 2011 - Springer
Abstract Phosphoinositide-dependent kinase-1 (PDK1) is a critical enzyme in the PI3K/AKT
pathway and to the activation of AGC family protein kinases, including S6K, SGK, and PKC …

Novel isoquinolone PDK1 inhibitors discovered through fragment-based lead discovery

MC Johnson, Q Hu, L Lingardo… - … of Computer-Aided …, 2011 - search.proquest.com
Abstract Phosphoinositide-dependent kinase-1 (PDK1) is a critical enzyme in the PI3K/AKT
pathway and to the activation of AGC family protein kinases, including S6K, SGK, and PKC …

Novel isoquinolone PDK1 inhibitors discovered through fragment-based lead discovery

MC Johnson, Q Hu, L Lingardo… - … of Computer-Aided …, 2011 - ui.adsabs.harvard.edu
Abstract Phosphoinositide-dependent kinase-1 (PDK1) is a critical enzyme in the PI3K/AKT
pathway and to the activation of AGC family protein kinases, including S6K, SGK, and PKC …

Novel isoquinolone PDK1 inhibitors discovered through fragment-based lead discovery

MC Johnson, Q Hu, L Lingardo… - … of computer-aided …, 2011 - pubmed.ncbi.nlm.nih.gov
Phosphoinositide-dependent kinase-1 (PDK1) is a critical enzyme in the PI3K/AKT pathway
and to the activation of AGC family protein kinases, including S6K, SGK, and PKC …

Novel isoquinolone PDK1 inhibitors discovered through fragment-based lead discovery

MC Johnson, Q Hu, L Lingardo, RA Ferre… - Journal of Computer …, 2011 - infona.pl
Phosphoinositide-dependent kinase-1 (PDK1) is a critical enzyme in the PI3K/AKT pathway
and to the activation of AGC family protein kinases, including S6K, SGK, and PKC …

Novel isoquinolone PDK1 inhibitors discovered through fragment-based lead discovery

MC Johnson, Q Hu, L Lingardo, RA Ferre… - Journal of Computer …, 2011 - hero.epa.gov
Abstract Phosphoinositide-dependent kinase-1 (PDK1) is a critical enzyme in the PI3K/AKT
pathway and to the activation of AGC family protein kinases, including S6K, SGK, and PKC …

Novel isoquinolone PDK1 inhibitors discovered through fragment-based lead discovery.

MC Johnson, Q Hu, L Lingardo… - … of Computer-Aided …, 2011 - search.ebscohost.com
Abstract Phosphoinositide-dependent kinase-1 (PDK1) is a critical enzyme in the PI3K/AKT
pathway and to the activation of AGC family protein kinases, including S6K, SGK, and PKC …

Novel isoquinolone PDK1 inhibitors discovered through fragment-based lead discovery.

MC Johnson, Q Hu, L Lingardo, RA Ferre… - Journal of Computer …, 2011 - europepmc.org
Phosphoinositide-dependent kinase-1 (PDK1) is a critical enzyme in the PI3K/AKT pathway
and to the activation of AGC family protein kinases, including S6K, SGK, and PKC …

[PDF][PDF] Novel isoquinolone PDK1 inhibitors discovered through fragment-based lead discovery

MC Johnson, Q Hu, L Lingardo, RA Ferre… - J Comput Aided Mol …, 2011 - academia.edu
Abstract Phosphoinositide-dependent kinase-1 (PDK1) is a critical enzyme in the PI3K/AKT
pathway and to the activation of AGC family protein kinases, including S6K, SGK, and PKC …

[PDF][PDF] Novel isoquinolone PDK1 inhibitors discovered through fragment-based lead discovery

MC Johnson, Q Hu, L Lingardo, RA Ferre… - J Comput Aided Mol …, 2011 - academia.edu
Abstract Phosphoinositide-dependent kinase-1 (PDK1) is a critical enzyme in the PI3K/AKT
pathway and to the activation of AGC family protein kinases, including S6K, SGK, and PKC …