Molecular switch for CLC-K Cl channel block/activation: Optimal pharmacophoric requirements towards high-affinity ligands

A Liantonio, A Picollo, G Carbonara… - Proceedings of the …, 2008 - National Acad Sciences
ClC-Ka and ClC-Kb Cl− channels are pivotal for renal salt reabsorption and water balance.
There is growing interest in identifying ligands that allow pharmacological interventions …

Molecular switch for CLC-K Cl-channel block/activation: optimal pharmacophoric requirements towards high-affinity ligands.

A Liantonio, A Picollo, G Carbonara… - Proceedings of the …, 2008 - europepmc.org
Abstract ClC-Ka and ClC-Kb Cl− channels are pivotal for renal salt reabsorption and water
balance. There is growing interest in identifying ligands that allow pharmacological …

[PDF][PDF] Molecular switch for CLC-K Cl channel block/activation: Optimal pharmacophoric requirements towards high-affinity ligands

A Liantonio, A Picollo, G Carbonara, G Fracchiolla… - PNAS, 2008 - researchgate.net
Results Effect of Rationally Designed Molecules on ClC-Ka. Effect of an NFA analog with
noncoplanar conformation. Recently, we showed that NFA (Fig. 1A) has a biphasic behavior …

Molecular Switch for CLC-K Cl⁻ Channel Block/Activation: Optimal Pharmacophoric Requirements Towards High-Affinity Ligands

A Liantonio, A Picollo, G Carbonara… - Proceedings of the …, 2008 - JSTOR
CIC-Ka and CIC-Kb Cl⁻ channels are pivotal for renal salt reabsorption and water balance.
There is growing interest in identifying ligands that allow pharmacological interventions …

[PDF][PDF] Molecular switch for CLC-K Cl channel block/activation: Optimal pharmacophoric requirements towards high-affinity ligands

A Liantonio, A Picollo, G Carbonara, G Fracchiolla… - PNAS, 2008 - academia.edu
Results Effect of Rationally Designed Molecules on ClC-Ka. Effect of an NFA analog with
noncoplanar conformation. Recently, we showed that NFA (Fig. 1A) has a biphasic behavior …

[HTML][HTML] Molecular switch for CLC-K Cl− channel block/activation: Optimal pharmacophoric requirements towards high-affinity ligands

A Liantonio, A Picollo, G Carbonara… - Proceedings of the …, 2008 - ncbi.nlm.nih.gov
Abstract ClC-Ka and ClC-Kb Cl− channels are pivotal for renal salt reabsorption and water
balance. There is growing interest in identifying ligands that allow pharmacological …

Molecular switch for CLC-K Cl- channel block/activation: Optimal pharmacophoric requirements towards high-affinity ligands

A Liantonio, A Picollo, G Carbonara… - Proceedings of the …, 2008 - ui.adsabs.harvard.edu
Abstract ClC-Ka and ClC-Kb Cl-channels are pivotal for renal salt reabsorption and water
balance. There is growing interest in identifying ligands that allow pharmacological …

Molecular switch for CLC-K Cl–channel block/activation: Optimal pharmacophoric requirements towards high-affinity ligands

A Liantonio, D Conte, GG Carbonara… - … OF THE NATIONAL …, 2008 - ricerca.uniba.it
ClC-Ka and ClC-Kb Cl (-) channels are pivotal for renal salt reabsorption and water balance.
There is growing interest in identifying ligands that allow pharmacological interventions …

Molecular switch for CLC-K Cl-channel block/activation: optimal pharmacophoric requirements towards high-affinity ligands

A Liantonio, A Picollo, G Carbonara… - Proceedings of the …, 2008 - pubmed.ncbi.nlm.nih.gov
ClC-Ka and ClC-Kb Cl (-) channels are pivotal for renal salt reabsorption and water balance.
There is growing interest in identifying ligands that allow pharmacological interventions …

[引用][C] Molecular switch for CLC-K Cl⁻ channel block/activation: Optimal pharmacophoric requirements towards high-affinity ligands

A Liantonio, A Picollo, G Carbonara, G Fracchiolla… - 2008