Triazole‐Pyridine Dicarbonitrile Targets Phosphodiesterase 4 to Induce Cytotoxicity in Lung Carcinoma Cells

HK Keerthy, S Mohan, Basappa… - Chemistry & …, 2019 - Wiley Online Library
Abstract Phosphodiesterase 4 (PDE4) is a key enzyme involved in the hydrolysis of cyclic
adenosine monophosphate (cAMP) and widely expressed in several types of cancers. The …

Triazole-Pyridine Dicarbonitrile Targets Phosphodiesterase 4 to Induce Cytotoxicity in Lung Carcinoma Cells

HK Keerthy, S Mohan… - Chemistry & …, 2019 - pubmed.ncbi.nlm.nih.gov
Phosphodiesterase 4 (PDE4) is a key enzyme involved in the hydrolysis of cyclic adenosine
monophosphate (cAMP) and widely expressed in several types of cancers. The inhibition of …

Triazole-Pyridine Dicarbonitrile Targets Phosphodiesterase 4 to Induce Cytotoxicity in Lung Carcinoma Cells.

HK Keerthy, S Mohan, H Bharathkumar… - Chemistry & …, 2019 - europepmc.org
Phosphodiesterase 4 (PDE4) is a key enzyme involved in the hydrolysis of cyclic adenosine
monophosphate (cAMP) and widely expressed in several types of cancers. The inhibition of …