[HTML][HTML] GBT021601, a next generation HbS polymerization inhibitor: results of safety, tolerability, pharmacokinetics and pharmacodynamics in adults living with sickle …

RCC Brown, A Redfern, E Lisbon, C Washington… - Blood, 2021 - Elsevier
Background: Sickle cell disease (SCD) is caused by polymerization of sickle hemoglobin
(HbS), resulting in red blood cell (RBC) sickling, RBC destruction, vaso-occlusion and end …

GBT021601, a Next Generation HbS Polymerization Inhibitor: Results of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Adults Living with Sickle …

R Brown, A Redfern, E Lisbon, C Washington, I Agodoa… - Blood, 2021 - ashpublications.org
Background: Sickle cell disease (SCD) is caused by polymerization of sickle hemoglobin
(HbS), resulting in red blood cell (RBC) sickling, RBC destruction, vaso-occlusion and end …