FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination
E Guo, Y Ishii, J Mueller, A Srivatsan… - Proceedings of the …, 2020 - National Acad Sciences
Synthetic lethality strategies for cancer therapy exploit cancer-specific genetic defects to
identify targets that are uniquely essential to the survival of tumor cells. Here we show …
identify targets that are uniquely essential to the survival of tumor cells. Here we show …
FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination.
E Guo, Y Ishii, J Mueller, A Srivatsan… - Proceedings of the …, 2020 - europepmc.org
Synthetic lethality strategies for cancer therapy exploit cancerspecific genetic defects to
identify targets that are uniquely essential to the survival of tumor cells. Here we show …
identify targets that are uniquely essential to the survival of tumor cells. Here we show …
FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination
E Guo, Y Ishii, J Mueller, A Srivatsan, T Gahman… - Proceedings of the …, 2020 - JSTOR
Synthetic lethality strategies for cancer therapy exploit cancer-specific genetic defects to
identify targets that are uniquely essential to the survival of tumor cells. Here we show …
identify targets that are uniquely essential to the survival of tumor cells. Here we show …
FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination
E Guo, Y Ishii, J Mueller, A Srivatsan… - Proceedings of the …, 2020 - discovery.ucl.ac.uk
Synthetic lethality strategies for cancer therapy exploit cancer-specific genetic defects to
identify targets that are uniquely essential to the survival of tumor cells. Here we show …
identify targets that are uniquely essential to the survival of tumor cells. Here we show …
[PDF][PDF] FEN1 endonuclease as a therapeutic target for human cancers with defects in
E Guo, Y Ishii, J Mueller - … of the National Academy of Sciences …, 2020 - scholar.archive.org
Synthetic lethality strategies for cancer therapy exploit cancerspecific genetic defects to
identify targets that are uniquely essential to the survival of tumor cells. Here we show …
identify targets that are uniquely essential to the survival of tumor cells. Here we show …
FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination
E Guo, Y Ishii, J Mueller, A Srivatsan… - Proceedings of the …, 2020 - pubmed.ncbi.nlm.nih.gov
Synthetic lethality strategies for cancer therapy exploit cancer-specific genetic defects to
identify targets that are uniquely essential to the survival of tumor cells. Here we show …
identify targets that are uniquely essential to the survival of tumor cells. Here we show …
FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination
E Guo, Y Ishii, J Mueller, A Srivatsan… - Proceedings of the …, 2020 - ui.adsabs.harvard.edu
Abstract Analysis of synthetic lethal relationships identified in Saccharomyces cerevisiae
was used to identify candidate therapeutic targets for cancers with BRCA1 or BRCA2 …
was used to identify candidate therapeutic targets for cancers with BRCA1 or BRCA2 …
FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination.
E Guo, Y Ishii, J Mueller, A Srivatsan… - Proceedings of the …, 2020 - escholarship.org
Synthetic lethality strategies for cancer therapy exploit cancer-specific genetic defects to
identify targets that are uniquely essential to the survival of tumor cells. Here we show …
identify targets that are uniquely essential to the survival of tumor cells. Here we show …
[HTML][HTML] FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination
E Guo, Y Ishii, J Mueller, A Srivatsan… - Proceedings of the …, 2020 - ncbi.nlm.nih.gov
Synthetic lethality strategies for cancer therapy exploit cancerspecific genetic defects to
identify targets that are uniquely essential to the survival of tumor cells. Here we show …
identify targets that are uniquely essential to the survival of tumor cells. Here we show …
FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination.
E Guo, Y Ishii, J Mueller, A Srivatsan… - Proceedings of the …, 2020 - europepmc.org
Synthetic lethality strategies for cancer therapy exploit cancer-specific genetic defects to
identify targets that are uniquely essential to the survival of tumor cells. Here we show …
identify targets that are uniquely essential to the survival of tumor cells. Here we show …