[HTML][HTML] Dual role of an N-terminal amyloidogenic mutation in apolipoprotein AI: destabilization of helix bundle and enhancement of fibril formation

E Adachi, H Nakajima, C Mizuguchi… - Journal of Biological …, 2013 - ASBMB
A number of naturally occurring mutations of apolipoprotein (apo) AI, the major protein of
HDL, are known to be associated with hereditary amyloidosis and atherosclerosis. Here, we …

[HTML][HTML] Dual Role of an N-terminal Amyloidogenic Mutation in Apolipoprotein AI: DESTABILIZATION OF HELIX BUNDLE AND ENHANCEMENT OF FIBRIL …

E Adachi, H Nakajima, C Mizuguchi… - The Journal of …, 2013 - ncbi.nlm.nih.gov
Results: The G26R mutation destabilizes the N-terminal helix bundle in full-length protein
and also enhances amyloid fibril formation by the N-terminal 1–83 fragment. Conclusion …

Dual role of an N-terminal amyloidogenic mutation in apolipoprotein AI: destabilization of helix bundle and enhancement of fibril formation

E Adachi, H Nakajima, C Mizuguchi… - The Journal of …, 2013 - pubmed.ncbi.nlm.nih.gov
A number of naturally occurring mutations of apolipoprotein (apo) AI, the major protein of
HDL, are known to be associated with hereditary amyloidosis and atherosclerosis. Here, we …

[HTML][HTML] Dual Role of an N-terminal Amyloidogenic Mutation in Apolipoprotein AI: DESTABILIZATION OF HELIX BUNDLE AND ENHANCEMENT OF FIBRIL …

E Adachi, H Nakajima, C Mizuguchi… - Journal of Biological …, 2013 - Elsevier
A number of naturally occurring mutations of apolipoprotein (apo) AI, the major protein of
HDL, are known to be associated with hereditary amyloidosis and atherosclerosis. Here, we …

Dual role of an N-terminal amyloidogenic mutation in apolipoprotein AI: destabilization of helix bundle and enhancement of fibril formation.

E Adachi, H Nakajima, C Mizuguchi… - The Journal of …, 2012 - europepmc.org
A number of naturally occurring mutations of apolipoprotein (apo) AI, the major protein of
HDL, are known to be associated with hereditary amyloidosis and atherosclerosis. Here, we …

[引用][C] Dual Role of an N-terminal Amyloidogenic Mutation in Apolipoprotein AI

E Adachi, H Nakajima, C Mizuguchi… - Journal of Biological …, 2013 - cir.nii.ac.jp

Dual role of an N-terminal amyloidogenic mutation in apolipoprotein AI: destabilization of helix bundle and enhancement of fibril formation.

E Adachi, H Nakajima, C Mizuguchi… - The Journal of …, 2012 - europepmc.org
A number of naturally occurring mutations of apolipoprotein (apo) AI, the major protein of
HDL, are known to be associated with hereditary amyloidosis and atherosclerosis. Here, we …