[HTML][HTML] Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients

JA Abrantes, A Solms, D Garmann, EI Nielsen… - …, 2020 - ncbi.nlm.nih.gov
Pharmacokinetic-based prophylaxis of replacement factor VIII (FVIII) products has been
encouraged in recent years, but the relationship between exposure (factor VIII activity) and …

[HTML][HTML] Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients

JA Abrantes, A Solms, D Garmann, EI Nielsen… - …, 2020 - haematologica.org
Pharmacokinetic-based prophylaxis of replacement factor VIII (FVIII) products has been
encouraged in recent years, but the relationship between exposure (factor VIII activity) and …

[PDF][PDF] Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients

JA Abrantes, A Solms, D Garmann, EI Nielsen… - 2019 - academia.edu
Pharmacokinetic-based prophylaxis of replacement factor VIII products has been
encouraged in the past years, but the exposure (factor VIII activity)-response (bleeding …

Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients.

JA Abrantes, A Solms, D Garmann, EI Nielsen… - …, 2019 - europepmc.org
Pharmacokinetic-based prophylaxis of replacement factor VIII (FVIII) products has been
encouraged in recent years, but the relationship between exposure (factor VIII activity) and …

Basic HTML Version

JA Abrantes - haematologica, 2020 - digital.haematologica.org
individual PK parameters, a patient-specific dosing regi-men can be suggested. 13
Recently, the shift from standard prophylaxis to PK-based prophylaxis was facilitated by the …

Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients

JA Abrantes, A Solms, D Garmann… - …, 2020 - pubmed.ncbi.nlm.nih.gov
Pharmacokinetic-based prophylaxis of replacement factor VIII (FVIII) products has been
encouraged in recent years, but the relationship between exposure (factor VIII activity) and …

[PDF][PDF] Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients

MO KARLSSON - haematologica, 2020 - researchgate.net
Hemophilia A is an X-linked hereditary bleeding disorder caused by the deficiency of
coagulation factor VIII (FVIII). The severity of the disease is inversely correlated with the …

Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients

JA Abrantes, A Solms, D Garmann, EI Nielsen… - …, 2020 - diva-portal.org
Hemophilia A is an X-linked hereditary bleeding disorder caused by the deficiency of
coagulation factor VIII (FVIII). The severity of the disease is inversely correlated with the …

[HTML][HTML] Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients

JA Abrantes, A Solms, D Garmann, EI Nielsen… - …, 2020 - haematologica.org
Pharmacokinetic-based prophylaxis of replacement factor VIII (FVIII) products has been
encouraged in recent years, but the relationship between exposure (factor VIII activity) and …

Basic HTML Version

JA Abrantes - Haematologica, 2020 - digital.haematologica.org
individualization, a pre-defined FVIII activity target would not be required, in contrast to the
current implementation of PK-based dosing. Instead, the full model would be employed …