Discovery of new binders for DCAF1, an emerging ligase target in the targeted protein degradation field

A Vulpetti, P Holzer, N Schmiedeberg… - ACS Medicinal …, 2023 - ACS Publications
In this study, we describe the rapid identification of potent binders for the WD40 repeat
domain (WDR) of DCAF1. This was achieved by two rounds of iterative focused screening of …

Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field

A Vulpetti, P Holzer… - ACS Medicinal …, 2023 - research-collection.ethz.ch
In this study, we describe the rapid identification ofpotent bindersfor the WD40 repeat
domain (WDR) of DCAF1. This was achieved by tworounds of iterative focused screening of …

Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field.

A Vulpetti, P Holzer, N Schmiedeberg… - ACS Medicinal …, 2023 - europepmc.org
In this study, we describe the rapid identification of potent binders for the WD40 repeat
domain (WDR) of DCAF1. This was achieved by two rounds of iterative focused screening of …

Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field

A Vulpetti, P Holzer… - ACS medicinal …, 2023 - pubmed.ncbi.nlm.nih.gov
In this study, we describe the rapid identification of potent binders for the WD40 repeat
domain (WDR) of DCAF1. This was achieved by two rounds of iterative focused screening of …

Discovery of new binders for DCAF1, an emerging ligase target in the Targeted Protein Degradation field

A Vulpetti, P Holzer, N Schmiedeberg… - ACS Medicinal …, 2023 - oak.novartis.com
In this study, we describe the rapid identification of potent binders for the WD40 repeat
domain (WDR) of DCAF1. This was achieved by two rounds of iterative focused screening of …

Discovery of new binders for DCAF1, an emerging ligase target in the Targeted Protein Degradation field

A Vulpetti, P Holzer, N Schmiedeberg… - ACS Medicinal …, 2023 - oak.novartis.com
In this study, we describe the rapid identification of potent binders for the WD40 repeat
domain (WDR) of DCAF1. This was achieved by two rounds of iterative focused screening of …