[HTML][HTML] Characterization and mitigation of gene expression burden in mammalian cells

T Frei, F Cella, F Tedeschi, J Gutiérrez, GB Stan… - Nature …, 2020 - nature.com
Despite recent advances in circuit engineering, the design of genetic networks in
mammalian cells is still painstakingly slow and fraught with inexplicable failures. Here, we …

[PDF][PDF] Characterization and mitigation of gene expression burden in mammalian cells

T Frei, F Cella, F Tedeschi, J Gutiérrez, GB Stan… - academia.edu
Results Genetic circuits compete for limited shared resources. We reasoned that competition
for finite cellular resources would introduce an indirect coupling in the expression levels of …

Characterization and mitigation of gene expression burden in mammalian cells

T Frei, F Cella, F Tedeschi… - Nature …, 2020 - research-collection.ethz.ch
Despite recent advances in circuit engineering, the design of genetic networks in
mammalian cells is still painstakingly slow and fraught with inexplicable failures. Here, we …

Characterization and mitigation of gene expression burden in mammalian cells.

T Frei, F Cella, F Tedeschi, J Gutiérrez, GB Stan… - Nature …, 2020 - folia.unifr.ch
English Despite recent advances in circuit engineering, the design of genetic networks in
mammalian cells is still painstakingly slow and fraught with inexplicable failures. Here, we …

Characterization and mitigation of gene expression burden in mammalian cells.

T Frei, F Cella, F Tedeschi, J Gutiérrez, GB Stan… - Nature …, 2020 - sonar.ch
English Despite recent advances in circuit engineering, the design of genetic networks in
mammalian cells is still painstakingly slow and fraught with inexplicable failures. Here, we …

Characterization and mitigation of gene expression burden in mammalian cells

T Frei, F Cella, F Tedeschi, J Gutiérrez… - Nature …, 2020 - econpapers.repec.org
Despite recent advances in circuit engineering, the design of genetic networks in
mammalian cells is still painstakingly slow and fraught with inexplicable failures. Here, we …

Characterization and mitigation of gene expression burden in mammalian cells.

T Frei, F Cella, F Tedeschi, J Gutiérrez… - Nature …, 2020 - search.ebscohost.com
Despite recent advances in circuit engineering, the design of genetic networks in
mammalian cells is still painstakingly slow and fraught with inexplicable failures. Here, we …

Characterization and mitigation of gene expression burden in mammalian cells

T Frei, F Cella, F Tedeschi, J Gutiérrez… - Nature …, 2020 - ideas.repec.org
Despite recent advances in circuit engineering, the design of genetic networks in
mammalian cells is still painstakingly slow and fraught with inexplicable failures. Here, we …

Characterization and mitigation of gene expression burden in mammalian cells

T Frei, F Cella, F Tedeschi, J Gutiérrez… - Nature …, 2020 - ui.adsabs.harvard.edu
Despite recent advances in circuit engineering, the design of genetic networks in
mammalian cells is still painstakingly slow and fraught with inexplicable failures. Here, we …

Characterization and mitigation of gene expression burden in mammalian cells

T Frei, F Cella, F Tedeschi, J Gutiérrez, GB Stan… - Nature …, 2020 - cir.nii.ac.jp
抄録< jats: title> Abstract</jats: title>< jats: p> Despite recent advances in circuit engineering,
the design of genetic networks in mammalian cells is still painstakingly slow and fraught with …