Lysosome targeting chimeras (LYTACs) for the degradation of secreted and membrane proteins

S Banik, K Pedram, S Wisnovsky, N Riley, C Bertozzi - 2019 - chemrxiv.org
Targeted protein degradation is a powerful strategy to address the canonically undruggable
proteome. However, current technologies are limited to targets with cytosolically-accessible …
被引用次数：29 相关文章

Lysosome Targeting Chimeras (LYTACs) for the Degradation of Secreted and Membrane Proteins

S Banik, K Pedram, S Wisnovsky, N Riley, C Bertozzi - 2019 - europepmc.org
Targeted protein degradation is a powerful strategy to address the canonically undruggable
proteome. However, current technologies are limited to targets with cytosolically-accessible …
[PDF] archive.org

[PDF][PDF] Lysosome Targeting Chimeras (LYTACs) for the Degradation of Secreted and Membrane Proteins

S Banik, K Pedram, S Wisnovsky, N Riley, C Bertozzi - scholar.archive.org
Targeted protein degradation is a powerful strategy to address the canonically undruggable
proteome. However, current technologies are limited to targets with cytosolicallyaccessible …

Lysosome Targeting Chimeras (LYTACs) for the Degradation of Secreted and Membrane Proteins

S Banik, K Pedram, S Wisnovsky, N Riley, C Bertozzi - 2019 - chemrxiv.org
Targeted protein degradation is a powerful strategy to address the canonically undruggable
proteome. However, current technologies are limited to targets with cytosolically-accessible …
[PDF] archive.org

[PDF][PDF] Lysosome Targeting Chimeras (LYTACs) for the Degradation of Secreted and Membrane Proteins

S Banik, K Pedram, S Wisnovsky, N Riley, C Bertozzi - scholar.archive.org
The majority of therapies targeting individual proteins rely on specific activity-modulating
interactions with the target (eg, enzyme inhibition or ligand blocking), leaving major classes …

Lysosome Targeting Chimeras (LYTACs) for the Degradation of Secreted and Membrane Proteins

S Banik, K Pedram, S Wisnovsky, N Riley, C Bertozzi - 2019 - europepmc.org
Targeted protein degradation is a powerful strategy to address the canonically undruggable
proteome. However, current technologies are limited to targets with cytosolically-accessible …