Potent hydrazide-based HDAC inhibitors with a superior pharmacokinetic profile for efficient treatment of acute myeloid leukemia in vivo

Y Jiang, J Xu, K Yue, C Huang, M Qin… - Journal of Medicinal …, 2021 - ACS Publications
As “Michael acceptors” may induce promiscuous responses in mammalian cells by reacting
with various proteins, we modified the cinnamamide of our previous hydrazide-based HDAC …

Potent Hydrazide-Based HDAC Inhibitors with a Superior Pharmacokinetic Profile for Efficient Treatment of Acute Myeloid Leukemia In Vivo.

Y Jiang, J Xu, K Yue, C Huang, M Qin… - Journal of Medicinal …, 2021 - europepmc.org
As" Michael acceptors" may induce promiscuous responses in mammalian cells by reacting
with various proteins, we modified the cinnamamide of our previous hydrazide-based HDAC …

Potent Hydrazide-Based HDAC Inhibitors with a Superior Pharmacokinetic Profile for Efficient Treatment of Acute Myeloid Leukemia In Vivo

Y Jiang, J Xu, K Yue, C Huang… - Journal of …, 2022 - pubmed.ncbi.nlm.nih.gov
As" Michael acceptors" may induce promiscuous responses in mammalian cells by reacting
with various proteins, we modified the cinnamamide of our previous hydrazide-based HDAC …