Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination

L Loyal, J Braun, L Henze, B Kruse, M Dingeldey… - Science, 2021 - science.org
INTRODUCTION The clinical manifestations of COVID-19 vary from asymptomatic infection
to respiratory failure. Severe disease courses are primarily associated with advanced age …

[HTML][HTML] Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination

L Loyal, J Braun, L Henze, B Kruse… - Science (New York …, 2021 - ncbi.nlm.nih.gov
RESULTS We demonstrate broad CD4+ T cell cross-reactivity in unexposed individuals,
with the spike glycoprotein serving as one of the immunodominant targets. Although the N …

Cross-reactive CD4 + T cells enhance SARS-CoV-2 immune responses upon infection and vaccination

L Loyal, J Braun, L Henze, B Kruse, M Dingeldey… - Science, 2021 - cir.nii.ac.jp
抄録< jats: title> Cross-reactive T cells aid in the fight</jats: title>< jats: p> There is mounting
evidence that immunological memory after infection with seasonal human coronaviruses …

[HTML][HTML] Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination

L Loyal, J Braun, L Henze, B Kruse, M Dingeldey… - Science, 2021 - covid19.sld.cu
RESULTS We demonstrate broad CD4+ T cell cross-reactivity in unexposed individuals,
with the spike glycoprotein serving as one of the immunodominant targets. Although the N …

Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination

L Loyal, J Braun, L Henze, B Kruse, M Dingeldey… - sussex.figshare.com
The functional relevance of pre-existing cross-immunity to SARS-CoV-2 is a subject of
intense debate. Here, we show that human endemic coronavirus (HCoV)-reactive and SARS …

Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination

L Loyal, J Braun, L Henze, B Kruse… - … (New York, NY), 2021 - pubmed.ncbi.nlm.nih.gov
The functional relevance of preexisting cross-immunity to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is a subject of intense debate. Here, we show that human …

Cross-reactive CD4 (+) T cells enhance SARS-CoV-2 immune responses upon infection and vaccination

L Loyal, J Braun, L Henze, B Kruse, M Dingeldey… - Science, 2021 - edoc.mdc-berlin.de
The functional relevance of pre-existing cross-immunity to SARS-CoV-2 is a subject of
intense debate. Here, we show that human endemic coronavirus (HCoV)-reactive and SARS …

[HTML][HTML] Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination

L Loyal, J Braun, L Henze, B Kruse, M Dingeldey… - 2021 - europepmc.org
While evidence for pre-existing SARS-CoV-2-cross-reactive CD4+ T cells in unexposed
individuals is increasing, their functional significance remains unclear. Here, we …

Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination

L Loyal, J Braun, L Henze, B Kruse, M Dingeldey… - 2021 - pesquisa.bvsalud.org
While evidence for pre-existing SARS-CoV-2-cross-reactive CD4+ T cells in unexposed
individuals is increasing, their functional significance remains unclear. Here, we …

Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination

L Loyal, J Braun, L Henze, B Kruse, M Dingeldey… - medRxiv, 2021 - medrxiv.org
While evidence for pre-existing SARS-CoV-2-cross-reactive CD4+ T cells in unexposed
individuals is increasing, their functional significance remains unclear. Here, we …