Folates, in the form of tetrahydrolates, serve as cofactors for enzymes in a biological network
of metabolic pathways that are necessary for the de novo synthesis of purines, thymidylate …

Results: Shmt1+/-mice fed vitamin B12 and folic acid-deficient diets, as well as dietary folic
acid and nucleoside-supplemented diets showed significantly lower staggered rotarod …